Lineage for d1w6ud_ (1w6u D:)

  1. Root: SCOP 1.75
  2. 814173Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 819418Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 819419Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (12 families) (S)
  5. 819736Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (70 proteins)
    also known as short-chain dehydrogenases and SDR family
    parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
  6. 819829Protein 2,4-dienoyl-CoA reductase, mitochondrial (DECR) [117421] (1 species)
  7. 819830Species Human (Homo sapiens), [TaxId:9606] [117422] (3 PDB entries)
    Uniprot Q16698 35-328
  8. 819834Domain d1w6ud_: 1w6u D: [114291]
    complexed with hxc, nap

Details for d1w6ud_

PDB Entry: 1w6u (more details), 1.75 Å

PDB Description: structure of human decr ternary complex
PDB Compounds: (D:) 2,4-dienoyl-coa reductase,mitochondrial precursor

SCOP Domain Sequences for d1w6ud_:

Sequence, based on SEQRES records: (download)

>d1w6ud_ c.2.1.2 (D:) 2,4-dienoyl-CoA reductase, mitochondrial (DECR) {Human (Homo sapiens), [TaxId: 9606]}
mntealqskffsplqkamlppnsfqgkvafitgggtglgkgmttllsslgaqcviasrkm
dvlkataeqissqtgnkvhaiqcdvrdpdmvqntvselikvaghpnivinnaagnfispt
erlspnawktitdivlngtafvtleigkqlikaqkgaaflsittiyaetgsgfvvpsasa
kagveamskslaaewgkygmrfnviqpgpiktkgafsrldptgtfekemigripcgrlgt
veelanlaaflcsdyaswingavikfdggeevlisgefndlrkvtkeqwdtiee

Sequence, based on observed residues (ATOM records): (download)

>d1w6ud_ c.2.1.2 (D:) 2,4-dienoyl-CoA reductase, mitochondrial (DECR) {Human (Homo sapiens), [TaxId: 9606]}
mntealqskffsplqkamlppnsfqgkvafitgggtglgkgmttllsslgaqcviasrkm
dvlkataeqissqtgnkvhaiqcdvrdpdmvqntvselikvaghpnivinnaagnfispt
erlspnawktitdivlngtafvtleigkqlikaqkgaaflsittiyaetgsgfvvpsasa
kagveamskslaaewgkygmrfnviqpgpiktfekemigripcgrlgtveelanlaaflc
sdyaswingavikfdggeevlisgefndlrkvtkeqwdtiee

SCOP Domain Coordinates for d1w6ud_:

Click to download the PDB-style file with coordinates for d1w6ud_.
(The format of our PDB-style files is described here.)

Timeline for d1w6ud_: