Class c: Alpha and beta proteins (a/b) [51349] (147 folds) |
Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily) core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456 The nucleotide-binding modes of this and the next two folds/superfamilies are similar |
Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (12 families) |
Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (70 proteins) also known as short-chain dehydrogenases and SDR family parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7 |
Protein 2,4-dienoyl-CoA reductase, mitochondrial (DECR) [117421] (1 species) |
Species Human (Homo sapiens), [TaxId:9606] [117422] (3 PDB entries) Uniprot Q16698 35-328 |
Domain d1w6ud_: 1w6u D: [114291] complexed with hxc, nap |
PDB Entry: 1w6u (more details), 1.75 Å
SCOP Domain Sequences for d1w6ud_:
Sequence, based on SEQRES records: (download)
>d1w6ud_ c.2.1.2 (D:) 2,4-dienoyl-CoA reductase, mitochondrial (DECR) {Human (Homo sapiens), [TaxId: 9606]} mntealqskffsplqkamlppnsfqgkvafitgggtglgkgmttllsslgaqcviasrkm dvlkataeqissqtgnkvhaiqcdvrdpdmvqntvselikvaghpnivinnaagnfispt erlspnawktitdivlngtafvtleigkqlikaqkgaaflsittiyaetgsgfvvpsasa kagveamskslaaewgkygmrfnviqpgpiktkgafsrldptgtfekemigripcgrlgt veelanlaaflcsdyaswingavikfdggeevlisgefndlrkvtkeqwdtiee
>d1w6ud_ c.2.1.2 (D:) 2,4-dienoyl-CoA reductase, mitochondrial (DECR) {Human (Homo sapiens), [TaxId: 9606]} mntealqskffsplqkamlppnsfqgkvafitgggtglgkgmttllsslgaqcviasrkm dvlkataeqissqtgnkvhaiqcdvrdpdmvqntvselikvaghpnivinnaagnfispt erlspnawktitdivlngtafvtleigkqlikaqkgaaflsittiyaetgsgfvvpsasa kagveamskslaaewgkygmrfnviqpgpiktfekemigripcgrlgtveelanlaaflc sdyaswingavikfdggeevlisgefndlrkvtkeqwdtiee
Timeline for d1w6ud_: