Lineage for d1w6ja1 (1w6j A:6-99,A:379-732)

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 2004058Fold a.102: alpha/alpha toroid [48207] (6 superfamilies)
    multihelical; up to seven alpha-hairpins are arranged in closed circular array; there may be sequence similarities between different superfamilies
  4. 2004426Superfamily a.102.4: Terpenoid cyclases/Protein prenyltransferases [48239] (5 families) (S)
  5. 2004455Family a.102.4.2: Terpene synthases [48243] (2 protein domains)
    consists of two toroid domains: one of six and one of five hairpins
  6. 2004456Protein Lanosterol synthase [116989] (1 species)
  7. 2004457Species Human (Homo sapiens) [TaxId:9606] [116990] (2 PDB entries)
    Uniprot P48449
  8. 2004460Domain d1w6ja1: 1w6j A:6-99,A:379-732 [114269]
    complexed with bog, c14, r71

Details for d1w6ja1

PDB Entry: 1w6j (more details), 2.2 Å

PDB Description: Structure of human OSC in complex with Ro 48-8071
PDB Compounds: (A:) lanosterol synthase

SCOPe Domain Sequences for d1w6ja1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1w6ja1 a.102.4.2 (A:6-99,A:379-732) Lanosterol synthase {Human (Homo sapiens) [TaxId: 9606]}
clrrrggpyktepatdlgrwrlncergrqtwtylqderagreqtgleayalgldtknyfk
dlpkahtafegalngmtfyvglqaedghwtgdygXqgtngsqiwdtafaiqalleagghh
rpefssclqkaheflrlsqvpdnppdyqkyyrqmrkggfsfstldcgwivsdctaealka
vlllqekcphvtehiprerlcdavavllnmrnpdggfatyetkrgghllellnpsevfgd
imidytyvectsavmqalkyfhkrfpehraaeiretltqglefcrrqqradgswegswgv
cftygtwfgleafacmgqtyrdgtacaevsracdfllsrqmadggwgedfesceerrylq
saqsqihntcwammglmavrhpdieaqergvrcllekqlpngdwpqeniagvfnkscais
ytsyrnifpiwalgrfsqlyperalaghp

SCOPe Domain Coordinates for d1w6ja1:

Click to download the PDB-style file with coordinates for d1w6ja1.
(The format of our PDB-style files is described here.)

Timeline for d1w6ja1:

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Domains from same chain:
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d1w6ja2