SCOPe 2.08: Domain d1vpxm1: 1vpx M:1-204

Lineage for d1vpxm1 (1vpx M:1-204)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (34 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.10: Aldolase [51569] (9 families)
   Common fold covers whole protein structure

5. Family c.1.10.1: Class I aldolase [51570] (13 proteins)
   the catalytic lysine forms schiff-base intermediate with substrate
   possible link between the aldolase superfamily and the phosphate-binding beta/alpha barrels

6. Protein Decameric fructose-6-phosphate aldolase/transaldolase [75085] (3 species)
   forms helix-swapped pentamers

7. Species Thermotoga maritima [TaxId:2336] [117379] (1 PDB entry)
   Uniprot Q9WYD1

8. Domain d1vpxm1: 1vpx M:1-204 [113989]
   Other proteins in same PDB: d1vpxa2, d1vpxb2, d1vpxc2, d1vpxd2, d1vpxe2, d1vpxf2, d1vpxg2, d1vpxh2, d1vpxi2, d1vpxj2, d1vpxk2, d1vpxl2, d1vpxm2, d1vpxn2, d1vpxo2, d1vpxp2, d1vpxq2, d1vpxr2, d1vpxs2, d1vpxt2
   Structural genomics target
   complexed with gol, so4

Details for d1vpxm1

PDB Entry: 1vpx, 2.4 Å

PDB Description: Crystal structure of Transaldolase (EC 2.2.1.2) (TM0295) from Thermotoga maritima at 2.40 A resolution

PDB Compounds: (M:) PROTEIN (Transaldolase (EC 2.2.1.2))

SCOPe Domain Sequences for d1vpxm1:

Sequence, based on SEQRES records:

>d1vpxm1 c.1.10.1 (M:1-204) Decameric fructose-6-phosphate aldolase/transaldolase {Thermotoga maritima [TaxId: 2336]}
mkifldtanleeikkgvewgivdgvttnptliskegaefkqrvkeicdlvkgpvsaevvs
ldyegmvrearelaqiseyvvikipmtpdgikavktlsaegiktnvtlvfspaqailaak
agatyvspfvgrmddlsndgmrmlgeiveiynnygfeteiiaasirhpmhvveaalmgvd
ivtmpfavleklfkhpmtdlgier

Sequence, based on observed residues (ATOM records):

>d1vpxm1 c.1.10.1 (M:1-204) Decameric fructose-6-phosphate aldolase/transaldolase {Thermotoga maritima [TaxId: 2336]}
mkifldtanleeikkgvewgivdgvttnptliskrvkeicdlvkgpvsaevvsldyegmv
rearelaqiseyvvikipmtpdgikavktlsaegiktnvtlvfspaqailaakagatyvs
pfvgrmddlsndgmrmlgeiveiynnygfeteiiaasirhpmhvveaalmgvdivtmpfa
vleklfkhpmtdlgier

Timeline for d1vpxm1:

• d1vpxm1 first appeared in SCOP 1.71, called d1vpxm_
  
• d1vpxm1 appears in SCOPe 2.07