SCOPe 2.01: Domain d1upwa_: 1upw A:

Lineage for d1upwa_ (1upw A:)

1. Root: SCOPe 2.01

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Oxysterols receptor LXR-beta [89149] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [89150] (6 PDB entries)
   Uniprot P55055 219-461

8. Domain d1upwa_: 1upw A: [113399]
   complexed with 444

Details for d1upwa_

PDB Entry: 1upw, 2.4 Å

PDB Description: crystal structure of the human liver x receptor beta ligand binding domain in complex with a synthetic agonist

PDB Compounds: (A:) oxysterols receptor lxr-beta

SCOPe Domain Sequences for d1upwa_:

Sequence, based on SEQRES records:

>d1upwa_ a.123.1.1 (A:) Oxysterols receptor LXR-beta {Human (Homo sapiens) [TaxId: 9606]}
qltaaqelmiqqlvaaqlqcnkrsfsdqpkvtpwplgadpqsrdarqqrfahftelaiis
vqeivdfakqvpgflqlgredqiallkastieimlletarrynhetecitflkdftyskd
dfhraglqvefinpifefsramrrlglddaeyalliainifsadrpnvqepgrvealqqp
yveallsytrikrpqdqlrfprmlmklvslrtlssvhseqvfalrlqdkklppllseiwd
vhe

Sequence, based on observed residues (ATOM records):

>d1upwa_ a.123.1.1 (A:) Oxysterols receptor LXR-beta {Human (Homo sapiens) [TaxId: 9606]}
qltaaqelmiqqlvaaqlqvtpwplgadpqsrdarqqrfahftelaiisvqeivdfakqv
pgflqlgredqiallkastieimlletarrynhetecitflkdftyskddfhraglqvef
inpifefsramrrlglddaeyalliainifsadrpnvqepgrvealqqpyveallsytri
krpqdqlrfprmlmklvslrtlssvhseqvfalrlqdkklppllseiwdvhe

Timeline for d1upwa_:

• d1upwa_ first appeared in SCOP 1.71
  
• d1upwa_ appears in SCOP 1.75
  
• d1upwa_ appears in SCOPe 2.02
  
• d1upwa_ appears in the current release, SCOPe 2.08