Lineage for d1unhe_ (1unh E:)

  1. Root: SCOPe 2.08
  2. 2685877Class a: All alpha proteins [46456] (290 folds)
  3. 2718075Fold a.74: Cyclin-like [47953] (1 superfamily)
    core: 5 helices; one helix is surrounded by the others
  4. 2718076Superfamily a.74.1: Cyclin-like [47954] (4 families) (S)
    duplication: consists of two domains of this fold
  5. 2718077Family a.74.1.1: Cyclin [47955] (9 proteins)
  6. 2718078Protein CDK5 activator 1 (NCK5a, p25) [74739] (1 species)
  7. 2718079Species Human (Homo sapiens) [TaxId:9606] [74740] (5 PDB entries)
    Uniprot Q15078 145-294
  8. 2718087Domain d1unhe_: 1unh E: [113323]
    Other proteins in same PDB: d1unha_, d1unhb_
    complexed with ixm

Details for d1unhe_

PDB Entry: 1unh (more details), 2.35 Å

PDB Description: structural mechanism for the inhibition of cdk5-p25 by roscovitine, aloisine and indirubin.
PDB Compounds: (E:) Cyclin-dependent kinase 5 activator 1

SCOPe Domain Sequences for d1unhe_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1unhe_ a.74.1.1 (E:) CDK5 activator 1 (NCK5a, p25) {Human (Homo sapiens) [TaxId: 9606]}
stsellrclgeflcrrcyrlkhlsptdpvlwlrsvdrslllqgwqdqgfitpanvvflym
lcrdvissevgsdhelqavlltclylsysymgneisyplkpflvesckeafwdrclsvin
lmsskmlqinadphyftqvfsdlknesg

SCOPe Domain Coordinates for d1unhe_:

Click to download the PDB-style file with coordinates for d1unhe_.
(The format of our PDB-style files is described here.)

Timeline for d1unhe_: