Lineage for d1unha_ (1unh A:)

  1. Root: SCOP 1.71
  2. 595667Class d: Alpha and beta proteins (a+b) [53931] (286 folds)
  3. 611837Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 611838Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (7 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 611879Family d.144.1.7: Protein kinases, catalytic subunit [88854] (60 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 612141Protein Cyclin-dependent PK, CDK5 [88857] (1 species)
    CMGC group; CDKs subfamily; serine/threonine kinase
  7. 612142Species Human (Homo sapiens) [TaxId:9606] [88858] (4 PDB entries)
  8. 612147Domain d1unha_: 1unh A: [113320]
    Other proteins in same PDB: d1unhd_, d1unhe_

Details for d1unha_

PDB Entry: 1unh (more details), 2.35 Å

PDB Description: structural mechanism for the inhibition of cdk5-p25 by roscovitine, aloisine and indirubin.

SCOP Domain Sequences for d1unha_:

Sequence, based on SEQRES records: (download)

>d1unha_ d.144.1.7 (A:) Cyclin-dependent PK, CDK5 {Human (Homo sapiens)}
qkyeklekigegtygtvfkaknretheivalkrvrlddddegvpssalreicllkelkhk
nivrlhdvlhsdkkltlvfefcdqdlkkyfdscngdldpeivksflfqllkglgfchsrn
vlhrdlkpqnllinrngelklanfglarafgipvrcysaevvtlwyrppdvlfgaklyst
sidmwsagcifaelanagrplfpgndvddqlkrifrllgtpteeqwpsmtklpdykpypm
ypattslvnvvpklnatgrdllqnllkcnpvqrisaeealqhpyfsd

Sequence, based on observed residues (ATOM records): (download)

>d1unha_ d.144.1.7 (A:) Cyclin-dependent PK, CDK5 {Human (Homo sapiens)}
qkyeklekiygtvfkaknrheivalkrvrldgvpssalreicllkelkhknivrlhdvlh
sdkkltlvfefcdqdlkkyfdscngdldpeivksflfqllkglgfchsrnvlhrdlkpqn
llinrngelklanfglarafgipvrcysaevvtlwyrppdvlfgaklystsidmwsagci
faelanagrplfpgndvddqlkrifrllgtpteeqwpsmtklpdykpypmypattslvnv
vpklnatgrdllqnllkcnpvqrisaeealqhpyfsd

SCOP Domain Coordinates for d1unha_:

Click to download the PDB-style file with coordinates for d1unha_.
(The format of our PDB-style files is described here.)

Timeline for d1unha_: