Lineage for d1u8lb1 (1u8l B:1-113)

  1. Root: SCOP 1.71
  2. 546417Class b: All beta proteins [48724] (149 folds)
  3. 546418Fold b.1: Immunoglobulin-like beta-sandwich [48725] (25 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 546419Superfamily b.1.1: Immunoglobulin [48726] (4 families) (S)
  5. 546420Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (28 proteins)
  6. 546556Protein Immunoglobulin heavy chain variable domain, VH [88543] (20 species)
    VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 546557Species Engineered (including hybrid species) [88562] (52 PDB entries)
  8. 546597Domain d1u8lb1: 1u8l B:1-113 [113146]
    Other proteins in same PDB: d1u8la1, d1u8la2, d1u8lb2

Details for d1u8lb1

PDB Entry: 1u8l (more details), 2.6 Å

PDB Description: Crystal structure of the HIV-1 Cross Neutralizing Monoclonal Antibody 2F5 in complex with gp41 Peptide DLDRWAS

SCOP Domain Sequences for d1u8lb1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1u8lb1 b.1.1.1 (B:1-113) Immunoglobulin heavy chain variable domain, VH {Engineered (including hybrid species)}
ritlkesgpplvkptqtltltcsfsgfslsdfgvgvgwirqppgkalewlaiiysdddkr
yspslntrltitkdtsknqvvlvmtrvspvdtatyfcahrrgpttlfgvpiargpvnamd
vwgqgitvtiss

SCOP Domain Coordinates for d1u8lb1:

Click to download the PDB-style file with coordinates for d1u8lb1.
(The format of our PDB-style files is described here.)

Timeline for d1u8lb1:

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Domains from same chain:
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d1u8lb2