SCOPe 2.06: Domain d1u8aa_: 1u8a A:

Lineage for d1u8aa_ (1u8a A:)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (26 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.2: Shikimate kinase (AroK) [52566] (2 proteins)
   similar to the nucleotide/nucleoside kinases but acts on different substrate
   automatically mapped to Pfam PF01202

6. Protein Shikimate kinase (AroK) [52567] (4 species)

7. Species Mycobacterium tuberculosis [TaxId:1773] [75194] (11 PDB entries)
   Uniprot P95014

8. Domain d1u8aa_: 1u8a A: [113115]
   complexed with adp, cl, skm

Details for d1u8aa_

PDB Entry: 1u8a, 2.15 Å

PDB Description: crystal structure of mycobacterium tuberculosis shikimate kinase in complex with shikimate and adp at 2.15 angstrom resolution

PDB Compounds: (A:) Shikimate kinase

SCOPe Domain Sequences for d1u8aa_:

Sequence, based on SEQRES records:

>d1u8aa_ c.37.1.2 (A:) Shikimate kinase (AroK) {Mycobacterium tuberculosis [TaxId: 1773]}
apkavlvglpgsgkstigrrlakalgvglldtdvaieqrtgrsiadifatdgeqefrrie
edvvraaladhdgvlslgggavtspgvraalaghtvvyleisaaegvrrtggntvrplla
gpdraekyralmakraplyrrvatmrvdtnrrnpgavvrhilsrl

Sequence, based on observed residues (ATOM records):

>d1u8aa_ c.37.1.2 (A:) Shikimate kinase (AroK) {Mycobacterium tuberculosis [TaxId: 1773]}
apkavlvglpgsgkstigrrlakalgvglldtdvaieqrtgrsiadifatdgeqefrrie
edvvraaladhdgvlslgggavtspgvraalaghtvvyleisaaegvrrtggvrpllagp
draekyralmakraplyrrvatmrvdtnrrnpgavvrhilsrl

Timeline for d1u8aa_:

• d1u8aa_ first appeared in SCOP 1.71
  
• d1u8aa_ appears in SCOPe 2.05
  
• d1u8aa_ appears in SCOPe 2.07
  
• d1u8aa_ appears in the current release, SCOPe 2.08