SCOPe 2.08: Domain d1u80a_: 1u80 A:

Lineage for d1u80a_ (1u80 A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.72: Ribokinase-like [53612] (3 superfamilies)
   core: 3 layers: a/b/a; mixed beta-sheet of 8 strands, order 21345678, strand 7 is antiparallel to the rest
   potential superfamily: members of this fold have similar functions but different ATP-binding sites

4. Superfamily c.72.3: CoaB-like [102645] (2 families)
   combination of the Rossmann-like and Ribokinase-like topologies; mixed beta-sheet of 8 strands, order 32145678, strand 7 is antiparallel to the rest

5. Family c.72.3.1: CoaB-like [102646] (3 proteins)
   Pfam PF04127

6. Protein Coenzyme A biosynthesis bifunctional protein CoaBC, phosphopantothenoylcysteine synthase domain (CoaB) [117722] (1 species)

7. Species Escherichia coli [TaxId:562] [117723] (4 PDB entries)
   Uniprot P24285 181-404

8. Domain d1u80a_: 1u80 A: [113110]
   complexed with c5p, po4

Details for d1u80a_

PDB Entry: 1u80, 2.85 Å

PDB Description: phosphopantothenoylcysteine synthetase from e. coli, cmp complex

PDB Compounds: (A:) Coenzyme A biosynthesis bifunctional protein coaBC

SCOPe Domain Sequences for d1u80a_:

Sequence, based on SEQRES records:

>d1u80a_ c.72.3.1 (A:) Coenzyme A biosynthesis bifunctional protein CoaBC, phosphopantothenoylcysteine synthase domain (CoaB) {Escherichia coli [TaxId: 562]}
vndlkhlnimitagptrepldpvryisdhssgkmgfaiaaaaarrganvtlvsgpvslpt
ppfvkrvdvmtalemeaavnasvqqqnifigcaavadyraatvapekikkqatqgdelti
kmvknpdivagvaalkdhrpyvvgfaaetnnveeyarqkrirknldlicandvsqptqgf
nsdnnalhlfwqdgdkvlplerkellgqllldeivtrydeknr

Sequence, based on observed residues (ATOM records):

>d1u80a_ c.72.3.1 (A:) Coenzyme A biosynthesis bifunctional protein CoaBC, phosphopantothenoylcysteine synthase domain (CoaB) {Escherichia coli [TaxId: 562]}
vndlkhlnimitagptrepldpvryisdhssgkmgfaiaaaaarrganvtlvsgpvslpt
ppfvkrvdvmtalemeaavnasvqqqnifigcaavadyraatvapekikkeltikmvknp
divagvaalkdhrpyvvgfaaetnnveeyarqkrirknldlicandvsqptqgfnsdnna
lhlfwqdgdkvlplerkellgqllldeivtrydeknr

Timeline for d1u80a_:

• d1u80a_ first appeared in SCOP 1.71
  
• d1u80a_ appears in SCOPe 2.07