SCOP 1.75: Domain d1u7tc_: 1u7t C:

Lineage for d1u7tc_ (1u7t C:)

1. Root: SCOP 1.75

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (12 families)

5. Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (70 proteins)
   also known as short-chain dehydrogenases and SDR family
   parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7

6. Protein Type II 3-hydroxyacyl-CoA dehydrogenase [63933] (3 species)

7. Species Human (Homo sapiens) [TaxId:9606] [102152] (3 PDB entries)
   Uniprot Q99714

8. Domain d1u7tc_: 1u7t C: [113101]

Details for d1u7tc_

PDB Entry: 1u7t, 2 Å

PDB Description: crystal structure of abad/hsd10 with a bound inhibitor

PDB Compounds: (C:) 3-hydroxyacyl-CoA dehydrogenase type II

SCOP Domain Sequences for d1u7tc_:

Sequence; same for both SEQRES and ATOM records:

>d1u7tc_ c.2.1.2 (C:) Type II 3-hydroxyacyl-CoA dehydrogenase {Human (Homo sapiens) [TaxId: 9606]}
svkglvavitggasglglataerlvgqgasavlldlpnsggeaqakklgnncvfapadvt
sekdvqtalalakgkfgrvdvavncagiavasktynlkkgqthtledfqrvldvnlmgtf
nvirlvagemgqnepdqggqrgviintasvaafegqvgqaaysaskggivgmtlpiardl
apigirvmtiapglfgtplltslpekvrnflasqvpfpsrlgdpaeyahlvqaiienpfl
ngevirldgairmqp

Timeline for d1u7tc_:

• d1u7tc_ first appeared in SCOP 1.71
  
• d1u7tc_ appears in SCOP 1.73
  
• d1u7tc_ appears in SCOPe 2.01
  
• d1u7tc_ appears in the current release, SCOPe 2.08