SCOPe 2.01: Domain d1u6gc_: 1u6g C:

Lineage for d1u6gc_ (1u6g C:)

1. Root: SCOPe 2.01

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.118: alpha-alpha superhelix [48370] (24 superfamilies)
   multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix

4. Superfamily a.118.1: ARM repeat [48371] (24 families)

5. Family a.118.1.2: HEAT repeat [48385] (2 proteins)
   Pfam PF02985
   this is a repeat family; one repeat unit is 1b3u A:295-335 found in domain

6. Protein Cullin-associated NEDD8-dissociated protein 1 (Tip120) [117000] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [117001] (1 PDB entry)
   Uniprot Q86VP6 4-1210

8. Domain d1u6gc_: 1u6g C: [113066]
   Other proteins in same PDB: d1u6ga1, d1u6ga2, d1u6ga3, d1u6gb_
   complexed with zn

Details for d1u6gc_

PDB Entry: 1u6g, 3.1 Å

PDB Description: Crystal Structure of The Cand1-Cul1-Roc1 Complex

PDB Compounds: (C:) TIP120 protein

SCOPe Domain Sequences for d1u6gc_:

Sequence, based on SEQRES records:

>d1u6gc_ a.118.1.2 (C:) Cullin-associated NEDD8-dissociated protein 1 (Tip120) {Human (Homo sapiens) [TaxId: 9606]}
asyhisnllekmtssdkdfrfmatndlmtelqkdsikldddserkvvkmilklledknge
vqnlavkclgplvskvkeyqvetivdtlctnmlsdkeqlrdissiglktvigelppassg
salaanvckkitgrltsaiakqedvsvqlealdimadmlsrqggllvnfhpsiltcllpq
ltsprlavrkrtiialghlvmscgnivfvdliehllselskndsmsttrtyiqciaaisr
qaghrigeylekiiplvvkfcnvdddelreyciqafesfvrrcpkevyphvstiiniclk
yltydpnynyddededenamdadggddddqgsddeysddddmswkvrraaakcldavvst
rhemlpefyktvspalisrfkereenvkadvfhaylsllkqtrpvqswlcdpdameqget
pltmlqsqvpnivkalhkqmkeksvktrqccfnmltelvnvlpgaltqhipvlvpgiifs
lndkssssnlkidalsclyvilcnhspqvfhphvqalvppvvacvgdpfykitseallvt
qqlvkvirpldqpssfdatpyikdlftctikrlkaadidqevkeraiscmgqiicnlgdn
lgsdlpntlqiflerlkneitrlttvkaltliagsplkidlrpvlgegvpilasflrknq
ralklgtlsaldiliknysdsltaamidavldelpplisesdmhvsqmaisflttlakvy
psslskisgsilneliglvrspllqggalsamldffqalvvtgtnnlgymdllrmltgpv
ysqstalthkqsyysiakcvaaltracpkegpavvgqfiqdvknsrstdsirllallslg
evghhidlsgqlelksvileafsspseevksaasyalgsisvgnlpeylpfvlqeitsqp
krqylllhslkeiissasvvglkpyveniwalllkhcecaeegtrnvvaeclgkltlidp
etllprlkgylisgssyarssvvtavkftisdhpqpidpllkncigdflktledpdlnvr
rvalvtfnsaahnkpslirdlldtvlphlynetkvrkelirevemgpfkhtvddgldirk
aafecmytlldscldrldifeflnhvedglkdhydikmltflmlvrlstlcpsavlqrld
rlveplratcttkvkansvkqefekqdelkrsamravaalltipeaeksplmsefqsqis
snpelaa

Sequence, based on observed residues (ATOM records):

>d1u6gc_ a.118.1.2 (C:) Cullin-associated NEDD8-dissociated protein 1 (Tip120) {Human (Homo sapiens) [TaxId: 9606]}
asyhisnllekmtssdkdfrfmatndlmtelqkdsikldddserkvvkmilklledknge
vqnlavkclgplvskvkeyqvetivdtlctnmlsdkeqlrdissiglktvigelpsalaa
nvckkitgrltsaiakqedvsvqlealdimadmlsrqggllvnfhpsiltcllpqltspr
lavrkrtiialghlvmscfvdliehllselskndsmsttrtyiqciaaisrqaghrigey
lekiiplvvkfcnvdddelreyciqafesfvrrcpkevyphvstiiniclkyltydmswk
vrraaakcldavvstrhemlpefyktvspalisrfkereenvkadvfhaylsllkqtrpv
getpltmlqsqvpnivkalhkqmkeksvktrqccfnmltelvnvlpgaltqhipvlvpgi
ifslndkssssnlkidalsclyvilcnhspqvfhphvqalvppvvacvgdpfykitseal
lvtqqlvkvirpldqpssfdatpyikdlftctikrlkaadidqevkeraiscmgqiicnl
gdnlgsdlpntlqiflerlkneitrlttvkaltliagsplkidlrpvlgegvpilasflr
knqralklgtlsaldiliknysdsltaamidavldelpplisesdmhvsqmaisflttla
kvypsslskisgsilneliglvrspllqggalsamldffqalvvtgtnnlgymdllrmlt
gpvysqthkqsyysiakcvaaltracpkegpavvgqfiqdvknsrstdsirllallslge
vghhidlsgqlelksvileafsspseevksaasyalgsisvgnlpeylpfvlqeitsqpk
rqylllhslkeiissasvvglkpyveniwalllkhcecaeegtrnvvaeclgkltlidpe
tllprlkgylisgssyarssvvtavkftisdhpqpidpllkncigdflktledpdlnvrr
valvtfnsaahnkpslirdlldtvlphlynetkvrkelirevemgpfkhtvddgldirka
afecmytlldscldrldifeflnhvedglkdhydikmltflmlvrlstlcpsavlqrldr
lveplratcttkvkansvkqefekqdelkrsamravaalltipeaeksplmsefqsqiss
npelaa

Timeline for d1u6gc_:

• d1u6gc_ first appeared in SCOP 1.71
  
• d1u6gc_ appears in SCOP 1.75
  
• d1u6gc_ appears in SCOPe 2.02
  
• d1u6gc_ appears in the current release, SCOPe 2.08