Lineage for d1u5bb1 (1u5b B:14-204)

  1. Root: SCOP 1.71
  2. 570216Class c: Alpha and beta proteins (a/b) [51349] (134 folds)
  3. 581036Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465
  4. 581037Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (8 families) (S)
    there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
    two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules
  5. 581162Family c.36.1.7: Branched-chain alpha-keto acid dehydrogenase Pyr module [88741] (4 proteins)
    parent family to TK and PFOR
    heterodimeric protein related to TK; alpha-subunit is the PP module and the N-terminal domain of beta-subunit is the Pyr module
  6. 581166Protein Branched-chain alpha-keto acid dehydrogenase, Pyr module [88742] (2 species)
  7. 581167Species Human (Homo sapiens) [TaxId:9606] [88743] (14 PDB entries)
  8. 581171Domain d1u5bb1: 1u5b B:14-204 [113035]
    Other proteins in same PDB: d1u5ba_, d1u5bb2
    complexed with gol, k, mn, tdp

Details for d1u5bb1

PDB Entry: 1u5b (more details), 1.83 Å

PDB Description: crystal structure of the human mitochondrial branched-chain alpha- ketoacid dehydrogenase

SCOP Domain Sequences for d1u5bb1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1u5bb1 c.36.1.7 (B:14-204) Branched-chain alpha-keto acid dehydrogenase, Pyr module {Human (Homo sapiens)}

SCOP Domain Coordinates for d1u5bb1:

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Timeline for d1u5bb1:

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