SCOP 1.73: Domain d1tn8a_: 1tn8 A:

Lineage for d1tn8a_ (1tn8 A:)

1. Root: SCOP 1.73

2. Class a: All alpha proteins [46456] (258 folds)

3. Fold a.118: alpha-alpha superhelix [48370] (23 superfamilies)
   multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix

4. Superfamily a.118.6: Protein prenylyltransferase [48439] (1 family)

5. Family a.118.6.1: Protein prenylyltransferase [48440] (2 proteins)

6. Protein Protein farnesyltransferase alpha-subunit [48441] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [69093] (20 PDB entries)

8. Domain d1tn8a_: 1tn8 A: [112531]
   Other proteins in same PDB: d1tn8b_
   complexed with acy, fii, zn; mutant

Details for d1tn8a_

PDB Entry: 1tn8, 2.25 Å

PDB Description: Protein Farnesyltransferase Complexed with a H-Ras Peptide Substrate and a FPP Analog at 2.25A Resolution

PDB Compounds: (A:) Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit

SCOP Domain Sequences for d1tn8a_:

Sequence; same for both SEQRES and ATOM records:

>d1tn8a_ a.118.6.1 (A:) Protein farnesyltransferase alpha-subunit {Human (Homo sapiens) [TaxId: 9606]}
flsldsptyvlyrdraewadidpvpqndgpspvvqiiysekfrdvydyfravlqrderse
rafkltrdaielnaanytvwhfrrvllrslqkdlqeemnyiiaiieeqpknyqvwhhrrv
lvewlkdpsqelefiadilnqdaknyhawqhrqwviqefrlwdnelqyvdqllkedvrnn
svwnqrhfvisnttgysdravlerevqytlemiklvphnesawnylkgilqdrglsrypn
llnqlldlqpshsspyliaflvdiyedmlenqcdnkedilnkalelceilakekdtirke
ywryigrslqskhsresdipasv

Timeline for d1tn8a_:

• d1tn8a_ first appeared in SCOP 1.71
  
• d1tn8a_ appears in SCOP 1.75
  
• d1tn8a_ appears in the current release, SCOPe 2.08