SCOP 1.71: Domain d1tktb1: 1tkt B:7-427

Lineage for d1tktb1 (1tkt B:7-427)

1. Root: SCOP 1.71

2. Class e: Multi-domain proteins (alpha and beta) [56572] (48 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (6 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.2: Reverse transcriptase [56686] (2 proteins)

6. Protein HIV-1 reverse transcriptase [56689] (2 species)

7. Species Human immunodeficiency virus type 1 [TaxId:11676] [56690] (83 PDB entries)

8. Domain d1tktb1: 1tkt B:7-427 [112484]
   Other proteins in same PDB: d1tkta1
   complexed with h12, mg, po4

Details for d1tktb1

PDB Entry: 1tkt, 2.6 Å

PDB Description: crystal structure of hiv-1 reverse transcriptase in complex with gw426318

SCOP Domain Sequences for d1tktb1:

Sequence, based on SEQRES records:

>d1tktb1 e.8.1.2 (B:7-427) HIV-1 reverse transcriptase {Human immunodeficiency virus type 1}
tvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikkk
dstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpldedfrk
ytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqymdd
lyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpivl
pekdswtvndiqklvgklnwasqiypgikvrqlckllrgtkalteviplteeaelelaen
reilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvk
qlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklw
y

Sequence, based on observed residues (ATOM records):

>d1tktb1 e.8.1.2 (B:7-427) HIV-1 reverse transcriptase {Human immunodeficiency virus type 1}
tvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikkk
dstkwrklvdfrelnkrtqdfwphpaglkkkksvtvldvgdayfsvpldedfrkytafti
psinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqymddlyvgsd
leigqhrtkieelrqhllrwgppflwmgyelhpdkwtvqpivlpekdswtvndiqklvgk
lnwasqiypgikvrqlckllrgtkalteviplteeaelelaenreilkepvhgvyydpsk
dliaeiqkqgqgqwtyqiyqepfknlktgkyartndvkqlteavqkittesiviwgktpk
fklpiqketwetwwteywqatwipewefvntpplvklwy

Timeline for d1tktb1:

• d1tktb1 is new in SCOP 1.71
  
• d1tktb1 appears in SCOP 1.73
  
• d1tktb1 appears in the current release, SCOPe 2.08