SCOPe 2.08: Domain d1szrb1: 1szr B:37-43,B:284-408

Lineage for d1szrb1 (1szr B:37-43,B:284-408)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.49: Domain of alpha and beta subunits of F1 ATP synthase-like [50614] (4 superfamilies)
   barrel, closed; n=6, S=8; greek-key
   Many cradle-loop superfamilies may be homologous, according to PubMed 18457946

4. Superfamily b.49.2: Alanine racemase C-terminal domain-like [50621] (2 families)
   the barrel is decorated with additional structures

5. Family b.49.2.3: Eukaryotic ODC-like [88683] (2 proteins)
   barrel is open with strands 4 and 5 having swapped their positions, compared to the alanine racemase barrel

6. Protein Eukaryotic ornithine decarboxylase (ODC) [50625] (3 species)

7. Species Trypanosome (Trypanosoma brucei) [TaxId:5691] [50628] (5 PDB entries)
   Uniprot P07805

8. Domain d1szrb1: 1szr B:37-43,B:284-408 [112176]
   Other proteins in same PDB: d1szra2, d1szrb2, d1szrc2, d1szrd2
   complexed with orx, plg, pxp; mutant
   missing some secondary structures that made up less than one-third of the common domain

Details for d1szrb1

PDB Entry: 1szr, 2.15 Å

PDB Description: a dimer interface mutant of ornithine decarboxylase reveals structure of gem diamine intermediate

PDB Compounds: (B:) ornithine decarboxylase

SCOPe Domain Sequences for d1szrb1:

Sequence, based on SEQRES records:

>d1szrb1 b.49.2.3 (B:37-43,B:284-408) Eukaryotic ornithine decarboxylase (ODC) {Trypanosome (Trypanosoma brucei) [TaxId: 5691]}
gdpffvaXftlavnviakavtpgvqtdvgahaesnaqsfmyyvndgvygsfncilydhav
vrplpqrepipneklypssvwgptcdgldqiveryylpemqvgewllfedmgaytvvgts
sfngfqsptiyyv

Sequence, based on observed residues (ATOM records):

>d1szrb1 b.49.2.3 (B:37-43,B:284-408) Eukaryotic ornithine decarboxylase (ODC) {Trypanosome (Trypanosoma brucei) [TaxId: 5691]}
gdpffvaXftlavnviakavtqsfmyyvndgvygsfncilydhavvrplpqrepklypss
vwgptcdgldqiveryylpemqvgewllfedmgaytvvgtssfngfqsptiyyv

Timeline for d1szrb1:

• d1szrb1 first appeared in SCOP 1.71
  
• d1szrb1 appears in SCOPe 2.07