SCOPe 2.08: Domain d1s5ja2: 1s5j A:450-864

Lineage for d1s5ja2 (1s5j A:450-864)

1. Root: SCOPe 2.08

2. Class e: Multi-domain proteins (alpha and beta) [56572] (74 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (9 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.1: DNA polymerase I [56673] (5 proteins)
   in the multi-domain class (e), this applies to domains with different numbers of (sub)domains than the most common domain
   

6. Protein Family B DNA polymerase [56680] (7 species)

7. Species Sulfolobus solfataricus [TaxId:2287] [118192] (1 PDB entry)
   Uniprot P26811 40-864

8. Domain d1s5ja2: 1s5j A:450-864 [112041]
   Other proteins in same PDB: d1s5ja1
   complexed with mg, so4

Details for d1s5ja2

PDB Entry: 1s5j, 2.4 Å

PDB Description: Insight in DNA Replication: The crystal structure of DNA Polymerase B1 from the archaeon Sulfolobus solfataricus

PDB Compounds: (A:) DNA polymerase I

SCOPe Domain Sequences for d1s5ja2:

Sequence, based on SEQRES records:

>d1s5ja2 e.8.1.1 (A:450-864) Family B DNA polymerase {Sulfolobus solfataricus [TaxId: 2287]}
eistwvknlyywehrkrnwliplkeeilakssnirtsalikgkgykgavvidppagiffn
itvldfaslypsiirtwnlsyetvdiqqckkpyevkdetgevlhivcmdrpgitavitgl
lrdfrvkiykkkaknpnnseeqkllydvvqramkvfinatygvfgaetfplyaprvaesv
talgryvitstvkkareegltvlygdtdslfllnppknsleniikwvkttfnldlevdkt
ykfvafsglkknyfgvyqdgkvdikgmlvkkrntpefvkkvfnevkelmisinspndvke
ikrkivdvvkgsyeklknkgynldelafkvmlskpldaykkntpqhvkaalqlrpfgvnv
lprdiiyyvkvrskdgvkpvqlakvteidaekylealrstfeqilrafgvswdei

Sequence, based on observed residues (ATOM records):

>d1s5ja2 e.8.1.1 (A:450-864) Family B DNA polymerase {Sulfolobus solfataricus [TaxId: 2287]}
eistwvknlyywehrkrnwliplkeeilakssnavvidppagiffnitvldfaslypsii
rtwnlsyetvdiqqckkpyevkdetgevlhivcmdrpgitavitgllrdfrvkiykkkak
npnnseeqkllydvvqramkvfinatygvfgaetfplyaprvaesvtalgryvitstvkk
areegltvlygdtdslfllnppknsleniikwvkttfnldlevdktykfvafsnyfgvyq
dgkvdikgmlvvkkvfnevkelmisinspndvkeikrkivdvvkgsyeklkidaekylea
lrstfeqilrafgvswdei

Timeline for d1s5ja2:

• d1s5ja2 first appeared in SCOP 1.71
  
• d1s5ja2 appears in SCOPe 2.07