SCOPe 2.05: Domain d1ry8b_: 1ry8 B:

Lineage for d1ry8b_ (1ry8 B:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.7: NAD(P)-linked oxidoreductase [51430] (2 families)

5. Family c.1.7.1: Aldo-keto reductases (NADP) [51431] (16 proteins)
   Common fold covers whole protein structure

6. Protein Prostaglandin d2 11-ketoreductase (akr1c3) [102051] (1 species)
   Aldo-keto reductase family 1 member c3

7. Species Human (Homo sapiens) [TaxId:9606] [102052] (40 PDB entries)
   Uniprot P42330

8. Domain d1ry8b_: 1ry8 B: [111966]
   complexed with ndp, rut

Details for d1ry8b_

PDB Entry: 1ry8, 1.69 Å

PDB Description: prostaglandin f synthase complexed with nadph and rutin

PDB Compounds: (B:) Aldo-keto reductase family 1 member C3

SCOPe Domain Sequences for d1ry8b_:

Sequence; same for both SEQRES and ATOM records:

>d1ry8b_ c.1.7.1 (B:) Prostaglandin d2 11-ketoreductase (akr1c3) {Human (Homo sapiens) [TaxId: 9606]}
qqcvklndghfmpvlgfgtyappevprskalevtklaieagfrhidsahlynneeqvgla
irskiadgsvkredifytsklwstfhrpelvrpalenslkkaqldyvdlylihspmslkp
geelsptdengkvifdivdlcttweamekckdaglaksigvsnfnrrqlemilnkpglky
kpvcnqvechpyfnrsklldfckskdivlvaysalgsqrdkrwvdpnspvlledpvlcal
akkhkrtpalialryqlqrgvvvlaksyneqrirqnvqvfefqltaedmkaidgldrnlh
yfnsdsfashpnypysdey

Timeline for d1ry8b_:

• d1ry8b_ first appeared in SCOP 1.71
  
• d1ry8b_ appears in SCOPe 2.04
  
• d1ry8b_ appears in SCOPe 2.06
  
• d1ry8b_ appears in the current release, SCOPe 2.08