SCOPe 2.07: Domain d1ry0a_: 1ry0 A:

Lineage for d1ry0a_ (1ry0 A:)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.7: NAD(P)-linked oxidoreductase [51430] (2 families)

5. Family c.1.7.1: Aldo-keto reductases (NADP) [51431] (16 proteins)
   Common fold covers whole protein structure

6. Protein Prostaglandin d2 11-ketoreductase (akr1c3) [102051] (1 species)
   Aldo-keto reductase family 1 member c3

7. Species Human (Homo sapiens) [TaxId:9606] [102052] (50 PDB entries)
   Uniprot P42330

8. Domain d1ry0a_: 1ry0 A: [111963]
   complexed with nap, pg2

Details for d1ry0a_

PDB Entry: 1ry0, 1.69 Å

PDB Description: structure of prostaglandin f synthase with prostaglandin d2

PDB Compounds: (A:) Aldo-keto reductase family 1 member C3

SCOPe Domain Sequences for d1ry0a_:

Sequence; same for both SEQRES and ATOM records:

>d1ry0a_ c.1.7.1 (A:) Prostaglandin d2 11-ketoreductase (akr1c3) {Human (Homo sapiens) [TaxId: 9606]}
qqcvklndghfmpvlgfgtyappevprskalevtklaieagfrhidsahlynneeqvgla
irskiadgsvkredifytsklwstfhrpelvrpalenslkkaqldyvdlylihspmslkp
geelsptdengkvifdivdlcttweamekckdaglaksigvsnfnrrqlemilnkpglky
kpvcnqvechpyfnrsklldfckskdivlvaysalgsqrdkrwvdpnspvlledpvlcal
akkhkrtpalialryqlqrgvvvlaksyneqrirqnvqvfefqltaedmkaidgldrnlh
yfnsdsfashpnypysdey

Timeline for d1ry0a_:

• d1ry0a_ first appeared in SCOP 1.71
  
• d1ry0a_ appears in SCOPe 2.06
  
• d1ry0a_ appears in the current release, SCOPe 2.08