SCOPe 2.08: Domain d1rxda_: 1rxd A:

Lineage for d1rxda_ (1rxd A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.45: (Phosphotyrosine protein) phosphatases II [52798] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1423

4. Superfamily c.45.1: (Phosphotyrosine protein) phosphatases II [52799] (6 families)
   share with the family I the common active site structure with a circularly permuted topology

5. Family c.45.1.1: Dual specificity phosphatase-like [52800] (9 proteins)

6. Protein Protein tyrosine phosphatase type IVa [102418] (3 species)

7. Species Human (Homo sapiens), pr-1 [TaxId:9606] [117578] (1 PDB entry)
   Uniprot Q93096 9-160

8. Domain d1rxda_: 1rxd A: [111959]
   Structural genomics target

Details for d1rxda_

PDB Entry: 1rxd, 1.9 Å

PDB Description: crystal structure of human protein tyrosine phosphatase 4a1

PDB Compounds: (A:) protein tyrosine phosphatase type IVA, member 1; Protein tyrosine phosphatase IVA1

SCOPe Domain Sequences for d1rxda_:

Sequence, based on SEQRES records:

>d1rxda_ c.45.1.1 (A:) Protein tyrosine phosphatase type IVa {Human (Homo sapiens), pr-1 [TaxId: 9606]}
pvevtyknmrflithnptnatlnkfieelkkygvttivrvceatydttlvekegihvldw
pfddgappsnqivddwlslvkikfreepgcciavhcvaglgrapvlvalalieggmkyed
avqfirqkrrgafnskqllylekyrpkmrlrf

Sequence, based on observed residues (ATOM records):

>d1rxda_ c.45.1.1 (A:) Protein tyrosine phosphatase type IVa {Human (Homo sapiens), pr-1 [TaxId: 9606]}
pvevtyknmrflithnptnatlnkfieelkkygvttivrvceatydttlvekegihvldw
pfgappsnqivddwlslvkikfreepgcciavhcvaglgrapvlvalalieggmkyedav
qfirqkrrgafnskqllylekyrpkmrlrf

Timeline for d1rxda_:

• d1rxda_ first appeared in SCOP 1.71
  
• d1rxda_ appears in SCOPe 2.07