Lineage for d1rwp.1 (1rwp A:,B:)

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2854798Fold c.17: Caspase-like [52128] (1 superfamily)
    3 layers, a/b/a; core: mixed beta-sheet of 6 strands, order 213456, strand 6 is antiparallel to the rest
  4. 2854799Superfamily c.17.1: Caspase-like [52129] (3 families) (S)
    mature protein may be composed of two chains folded in a single domain
  5. 2854800Family c.17.1.1: Caspase catalytic domain [52130] (8 proteins)
  6. 2854910Protein Interleukin-1beta converting enzyme (a cysteine protease) [52133] (1 species)
  7. 2854911Species Human (Homo sapiens) [TaxId:9606] [52134] (14 PDB entries)
    Uniprot P29466 125-297,317-404
  8. 2854918Domain d1rwp.1: 1rwp A:,B: [111950]
    complexed with hqc

Details for d1rwp.1

PDB Entry: 1rwp (more details), 2.2 Å

PDB Description: Crystal structure of human caspase-1 in complex with 3-{6-[(8-hydroxy-quinoline-2-carbonyl)-amino]-2-thiophen-2-yl-hexanoylamino}-4-oxo-butyric acid
PDB Compounds: (A:) Interleukin-1 beta convertase, (B:) Interleukin-1 beta convertase

SCOPe Domain Sequences for d1rwp.1:

Sequence; same for both SEQRES and ATOM records: (download)

>g1rwp.1 c.17.1.1 (A:,B:) Interleukin-1beta converting enzyme (a cysteine protease) {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d1rwp.1:

Click to download the PDB-style file with coordinates for d1rwp.1.
(The format of our PDB-style files is described here.)

Timeline for d1rwp.1: