Lineage for d1rwn.1 (1rwn A:,B:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2100990Fold c.17: Caspase-like [52128] (1 superfamily)
    3 layers, a/b/a; core: mixed beta-sheet of 6 strands, order 213456, strand 6 is antiparallel to the rest
  4. 2100991Superfamily c.17.1: Caspase-like [52129] (3 families) (S)
    mature protein may be composed of two chains folded in a single domain
  5. 2100992Family c.17.1.1: Caspase catalytic domain [52130] (8 protein domains)
  6. 2101096Protein Interleukin-1beta converting enzyme (a cysteine protease) [52133] (1 species)
  7. 2101097Species Human (Homo sapiens) [TaxId:9606] [52134] (14 PDB entries)
    Uniprot P29466 125-297,317-404
  8. 2101100Domain d1rwn.1: 1rwn A:,B: [111948]
    complexed with 4qb

Details for d1rwn.1

PDB Entry: 1rwn (more details), 2 Å

PDB Description: Crystal structure of human caspase-1 in complex with 3-{2-ethyl-6-[4-(quinoxalin-2-ylamino)-benzoylamino]-hexanoylamino}-4-oxo-butyric acid
PDB Compounds: (A:) Interleukin-1 beta convertase, (B:) Interleukin-1 beta convertase

SCOPe Domain Sequences for d1rwn.1:

Sequence; same for both SEQRES and ATOM records: (download)

>g1rwn.1 c.17.1.1 (A:,B:) Interleukin-1beta converting enzyme (a cysteine protease) {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d1rwn.1:

Click to download the PDB-style file with coordinates for d1rwn.1.
(The format of our PDB-style files is described here.)

Timeline for d1rwn.1: