Lineage for d1rwk.1 (1rwk A:,B:)

  1. Root: SCOP 1.71
  2. 570216Class c: Alpha and beta proteins (a/b) [51349] (134 folds)
  3. 578329Fold c.17: Caspase-like [52128] (1 superfamily)
    3 layers, a/b/a; core: mixed beta-sheet of 6 strands, order 213456, strand 6 is antiparallel to the rest
  4. 578330Superfamily c.17.1: Caspase-like [52129] (2 families) (S)
    mature protein may be composed of two chains folded in a single domain
  5. 578331Family c.17.1.1: Caspase catalytic domain [52130] (7 proteins)
  6. 578408Protein Interleukin-1beta converting enzyme (a cysteine protease) [52133] (1 species)
  7. 578409Species Human (Homo sapiens) [TaxId:9606] [52134] (14 PDB entries)
  8. 578417Domain d1rwk.1: 1rwk A:,B: [111946]
    complexed with 158

Details for d1rwk.1

PDB Entry: 1rwk (more details), 2.3 Å

PDB Description: Crystal structure of human caspase-1 in complex with 3-(2-mercapto-acetylamino)-4-oxo-pentanoic acid

SCOP Domain Sequences for d1rwk.1:

Sequence; same for both SEQRES and ATOM records: (download)

>g1rwk.1 c.17.1.1 (A:,B:) Interleukin-1beta converting enzyme (a cysteine protease) {Human (Homo sapiens)}
tssgsegnvklcsleeaqriwkqksaeiypimdkssrtrlaliicneefdsiprrtgaev
ditgmtmllqnlgysvdvkknltasdmtteleafahrpehktsdstflvfmshgiregic
gkkhseqvpdilqlnaifnmlntkncpslkdkpkviiiqacrgdspgvvwfkdXaikkah
iekdfiafcsstpdnvswrhptmgsvfigrliehmqeyacscdveeifrkvrfsfeqpdg
raqmpttervtltrcfylfpgh

SCOP Domain Coordinates for d1rwk.1:

Click to download the PDB-style file with coordinates for d1rwk.1.
(The format of our PDB-style files is described here.)

Timeline for d1rwk.1: