SCOP 1.73: Domain d1rs0a2: 1rs0 A:243-452

Lineage for d1rs0a2 (1rs0 A:243-452)

1. Root: SCOP 1.73

2. Class c: Alpha and beta proteins (a/b) [51349] (141 folds)

3. Fold c.62: vWA-like [53299] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 6 strands, order 321456; strand 3 is antiparallel to the rest

4. Superfamily c.62.1: vWA-like [53300] (5 families)

5. Family c.62.1.1: Integrin A (or I) domain [53301] (10 proteins)

6. Protein Complement factor B domain [102541] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [102542] (5 PDB entries)

8. Domain d1rs0a2: 1rs0 A:243-452 [111931]
   Other proteins in same PDB: d1rs0a1
   complexed with dfp, iod, mg, na; mutant

Details for d1rs0a2

PDB Entry: 1rs0, 2.6 Å

PDB Description: crystal structure analysis of the bb segment of factor b complexed with di-isopropyl-phosphate (dip)

PDB Compounds: (A:) complement factor b

SCOP Domain Sequences for d1rs0a2:

Sequence, based on SEQRES records:

>d1rs0a2 c.62.1.1 (A:243-452) Complement factor B domain {Human (Homo sapiens) [TaxId: 9606]}
smniylvldgsdsigasnftgakkvlvnliekvasygvkpryglvtyatypkiwvkvsea
dssnadwvtkqlneinyedhklksgtntkkalqavysmmswpddvppegwnrtrhviilm
tdglhnmggdpitvideirdllyigkdrknpredyldvyvfgvgplvnqvninalaskkd
neqhvckvkdmecledvfyqmidesqslsl

Sequence, based on observed residues (ATOM records):

>d1rs0a2 c.62.1.1 (A:243-452) Complement factor B domain {Human (Homo sapiens) [TaxId: 9606]}
smniylvldgsdsigasnftgakkvlvnliekvasygvkpryglvtyatypkiwvkvsea
dssnadwvtkqlneinyedhklksgtntkkalqavysmmswpgwnrtrhviilmtdglhn
mggdpitvideirdllyigkdrnpredyldvyvfgvgplvnqvninalaskkdneqhvck
vkdmecledvfyqmidesqslsl

Timeline for d1rs0a2:

• d1rs0a2 first appeared in SCOP 1.71
  
• d1rs0a2 appears in SCOP 1.75
  
• d1rs0a2 appears in the current release, SCOPe 2.08