SCOPe 2.07: Domain d1r5kb_: 1r5k B:

Lineage for d1r5kb_ (1r5k B:)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Estrogen receptor alpha [48519] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48520] (82 PDB entries)
   Uniprot P03372 307-551

8. Domain d1r5kb_: 1r5k B: [111707]
   protein/DNA complex; complexed with gw5

Details for d1r5kb_

PDB Entry: 1r5k, 2.7 Å

PDB Description: Human Estrogen Receptor alpha Ligand-Binding Domain In Complex With GW5638

PDB Compounds: (B:) Estrogen receptor

SCOPe Domain Sequences for d1r5kb_:

Sequence, based on SEQRES records:

>d1r5kb_ a.123.1.1 (B:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
lalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrvp
gfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmveif
dmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitdt
lihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplydllleml

Sequence, based on observed residues (ATOM records):

>d1r5kb_ a.123.1.1 (B:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
lalsltadqmvsalldaeppilyseydfseasmmglltnladrelvhminwakrvpgfvd
ltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmveifdmll
atssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitdtlihl
makagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplydllleml

Timeline for d1r5kb_:

• d1r5kb_ first appeared in SCOP 1.71
  
• d1r5kb_ appears in SCOPe 2.06
  
• d1r5kb_ appears in the current release, SCOPe 2.08