SCOPe 2.06: Domain d1r5ga2: 1r5g A:110-374,A:449-478

Lineage for d1r5ga2 (1r5g A:110-374,A:449-478)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.127: Creatinase/aminopeptidase [55919] (1 superfamily)
   duplication: composed of two very similar alpha+beta folds

4. Superfamily d.127.1: Creatinase/aminopeptidase [55920] (2 families)

5. Family d.127.1.1: Creatinase/aminopeptidase [55921] (4 proteins)

6. Protein Methionine aminopeptidase [55924] (6 species)

7. Species Human (Homo sapiens) [TaxId:9606] [55927] (18 PDB entries)
   Uniprot P50579 110-478
   methionine aminopeptidase 2 contains insert domain with a circularly permuted "winged helix" fold

8. Domain d1r5ga2: 1r5g A:110-374,A:449-478 [111703]
   Other proteins in same PDB: d1r5ga1
   complexed with ao1, mn

Details for d1r5ga2

PDB Entry: 1r5g, 2 Å

PDB Description: Crystal Structure of MetAP2 complexed with A311263

PDB Compounds: (A:) Methionine aminopeptidase 2

SCOPe Domain Sequences for d1r5ga2:

Sequence; same for both SEQRES and ATOM records:

>d1r5ga2 d.127.1.1 (A:110-374,A:449-478) Methionine aminopeptidase {Human (Homo sapiens) [TaxId: 9606]}
kvqtdppsvpicdlypngvfpkgqeceypptqdgrtaawrttseekkaldqaseeiwndf
reaaeahrqvrkyvmswikpgmtmieicekledcsrklikenglnaglafptgcslnnca
ahytpnagdttvlqyddickidfgthisgriidcaftvtfnpkydtllkavkdatntgik
cagidvrlcdvgeaiqevmesyeveidgktyqvkpirnlnghsigqyrihagktvpiikg
geatrmeegevyaietfgstgkgvvXdikgsytaqfehtillrptckevvsrgddy

Timeline for d1r5ga2:

• d1r5ga2 first appeared in SCOP 1.71
  
• d1r5ga2 appears in SCOPe 2.05
  
• d1r5ga2 appears in SCOPe 2.07
  
• d1r5ga2 appears in the current release, SCOPe 2.08