Lineage for d1r0eb_ (1r0e B:)

  1. Root: SCOP 1.75
  2. 849709Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 874255Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 874256Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (7 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 874317Family d.144.1.7: Protein kinases, catalytic subunit [88854] (63 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 874838Protein Glycogen synthase kinase-3 beta (Gsk3b) [69823] (1 species)
    CMGC group; GSK3 subfamily; serine/threonine kinase
  7. 874839Species Human (Homo sapiens) [TaxId:9606] [69824] (16 PDB entries)
    Uniprot P49841 35-383
    Uniprot P49841 35-384
    Uniprot P49841 35-383 ! Uniprot P49841 35-384
  8. 874855Domain d1r0eb_: 1r0e B: [111664]
    complexed with dfn, flc

Details for d1r0eb_

PDB Entry: 1r0e (more details), 2.25 Å

PDB Description: Glycogen synthase kinase-3 beta in complex with 3-indolyl-4-arylmaleimide inhibitor
PDB Compounds: (B:) Glycogen synthase kinase-3 beta

SCOP Domain Sequences for d1r0eb_:

Sequence, based on SEQRES records: (download)

>d1r0eb_ d.144.1.7 (B:) Glycogen synthase kinase-3 beta (Gsk3b) {Human (Homo sapiens) [TaxId: 9606]}
skvttvvatpgqgpdrpqevsytdtkvigngsfgvvyqaklcdsgelvaikkvlqdkrfk
nrelqimrkldhcnivrlryffyssgekkdevylnlvldyvpetvyrvarhysrakqtlp
viyvklymyqlfrslayihsfgichrdikpqnllldpdtavlklcdfgsakqlvrgepnv
syicsryyrapelifgatdytssidvwsagcvlaelllgqpifpgdsgvdqlveiikvlg
tptreqiremnpnytefkfpqikahpwtkvfrprtppeaialcsrlleytptarltplea
cahsffdelrdpnvklpngrdtpalfnfttqelssnpplatilipphar

Sequence, based on observed residues (ATOM records): (download)

>d1r0eb_ d.144.1.7 (B:) Glycogen synthase kinase-3 beta (Gsk3b) {Human (Homo sapiens) [TaxId: 9606]}
skvttvvatpgqgpdrpqevsytdtkvigngsfgvvyqaklcdsgelvaikkvlqdkrfk
nrelqimrkldhcnivrlryffyssevylnlvldyvpetvyrvarhysrakqtlpviyvk
lymyqlfrslayihsfgichrdikpqnllldpdtavlklcdfgsakqlvrgepnvsyics
ryyrapelifgatdytssidvwsagcvlaelllgqpifpgdsgvdqlveiikvlgtptre
qiremnpnytefkfpqikahpwtkvfrprtppeaialcsrlleytptarltpleacahsf
fdelrdpnvklpngrdtpalfnfttqelssnpplatilipphar

SCOP Domain Coordinates for d1r0eb_:

Click to download the PDB-style file with coordinates for d1r0eb_.
(The format of our PDB-style files is described here.)

Timeline for d1r0eb_: