Lineage for Family g.37.1.4: HkH motif-containing C2H2 finger

  1. Root: SCOPe 2.06
  2. 2256768Class g: Small proteins [56992] (94 folds)
  3. 2261821Fold g.37: beta-beta-alpha zinc fingers [57666] (1 superfamily)
    simple fold, consisting of the N-terminal beta-hairpin and C-terminal alpha-helical region; each part provides two zinc-coordinating residues with the observed sequences including C2H2, C2HC and CHHC
  4. 2261822Superfamily g.37.1: beta-beta-alpha zinc fingers [57667] (8 families) (S)
  5. 2262160Family g.37.1.4: HkH motif-containing C2H2 finger [111436] (4 proteins)
    putative dsRNA-specific zinc finger with a helix-kink-helix (HkH) motif; the kink results from the incompatibility of the cation-coordinating H-x5-H motif with a regular alpha-helix and contributes to RNA recognition

Proteins:

  1. 2262161dsRNA-binding protein ZFa (ZNF346, JAZ) [161154] (1 species)
  2. 2262165Spliceosomal protein U1C [111437] (1 species)
  3. 2262168Zinc finger homeobox protein 4, ZFHX4 [161156] (1 species)
  4. 2262171Zinc finger protein 593, ZNF593 [144151] (1 species)

More info for Family g.37.1.4: HkH motif-containing C2H2 finger

Timeline for Family g.37.1.4: HkH motif-containing C2H2 finger: