Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOPe 2.06
  2. 2170735Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2218047Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2218048Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2218179Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2220777Protein Tyrosine-protein kinase Itk/Tsk [111194] (1 species)
    PTK group; Tec/Atk subfamily; non-membrane spanning protein tyrosine kinase
  7. 2220778Species Human (Homo sapiens) [TaxId:9606] [111195] (33 PDB entries)
    Uniprot Q08881 357-619

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

  1. Domain(s) for 1sm2:
    1. 2220814Domain d1sm2a_: 1sm2 A: [105754]
      complexed with stu
    2. 2220815Domain d1sm2b_: 1sm2 B: [105755]
      complexed with stu
  2. Domain(s) for 1snu:
    1. 2220821Domain d1snua_: 1snu A: [105829]
      complexed with stu
    2. 2220822Domain d1snub_: 1snu B: [105830]
      complexed with stu
  3. Domain(s) for 1snx:
    1. 2220833Domain d1snxa_: 1snx A: [105831]
    2. 2220834Domain d1snxb_: 1snx B: [105832]
  4. Domain(s) for 3miy:
    1. 2220785Domain d3miya1: 3miy A:357-619 [181293]
      Other proteins in same PDB: d3miya2, d3miyb2
      automated match to d1sm2a_
      complexed with b49
    2. 2220786Domain d3miyb1: 3miy B:357-619 [181294]
      Other proteins in same PDB: d3miya2, d3miyb2
      automated match to d1sm2a_
      complexed with b49
  5. Domain(s) for 3mj1:
  6. Domain(s) for 3mj2:
  7. Domain(s) for 3qgw:
    1. 2220809Domain d3qgwa_: 3qgw A: [233325]
      automated match to d4kioc_
      complexed with l7a, pqc
    2. 2220810Domain d3qgwb_: 3qgw B: [233324]
      automated match to d4kioc_
      complexed with l7a, pqc
  8. Domain(s) for 3qgy:
    1. 2220799Domain d3qgya1: 3qgy A:357-618 [233326]
      Other proteins in same PDB: d3qgya2, d3qgyb2
      automated match to d4kioc_
      complexed with l7o, pqc
    2. 2220800Domain d3qgyb1: 3qgy B:357-616 [233327]
      Other proteins in same PDB: d3qgya2, d3qgyb2
      automated match to d4kioc_
      complexed with l7o, pqc
  9. Domain(s) for 3t9t:
  10. Domain(s) for 3v5j:
    1. 2220817Domain d3v5ja1: 3v5j A:357-618 [195400]
      Other proteins in same PDB: d3v5ja2, d3v5jb2
      automated match to d1sm2a_
      complexed with 0f2, so4
    2. 2220818Domain d3v5jb1: 3v5j B:357-620 [201197]
      Other proteins in same PDB: d3v5ja2, d3v5jb2
      automated match to d3v8wb_
      complexed with 0f2, so4
  11. Domain(s) for 3v5l:
    1. 2220790Domain d3v5la1: 3v5l A:357-616 [201198]
      Other proteins in same PDB: d3v5la2, d3v5lb2, d3v5lc2, d3v5ld2
      automated match to d3v8wb_
      complexed with 0g1, so4
    2. 2220791Domain d3v5lb1: 3v5l B:357-619 [195401]
      Other proteins in same PDB: d3v5la2, d3v5lb2, d3v5lc2, d3v5ld2
      automated match to d1sm2a_
      complexed with 0g1, so4
    3. 2220792Domain d3v5lc1: 3v5l C:357-616 [201199]
      Other proteins in same PDB: d3v5la2, d3v5lb2, d3v5lc2, d3v5ld2
      automated match to d3v8wb_
      complexed with 0g1, so4
    4. 2220793Domain d3v5ld1: 3v5l D:357-619 [201200]
      Other proteins in same PDB: d3v5la2, d3v5lb2, d3v5lc2, d3v5ld2
      automated match to d3v8wb_
      complexed with 0g1, so4
  12. Domain(s) for 3v8t:
    1. 2220795Domain d3v8ta1: 3v8t A:357-618 [217703]
      Other proteins in same PDB: d3v8ta2, d3v8tb2
      automated match to d3v8wb_
      complexed with 477, so4
    2. 2220796Domain d3v8tb1: 3v8t B:357-619 [217704]
      Other proteins in same PDB: d3v8ta2, d3v8tb2
      automated match to d3v8wb_
      complexed with 477, so4
  13. Domain(s) for 3v8w:
    1. 2220812Domain d3v8wa1: 3v8w A:357-619 [201211]
      Other proteins in same PDB: d3v8wa2, d3v8wb2
      automated match to d3v8wb_
      complexed with 0g2, so4
    2. 2220813Domain d3v8wb1: 3v8w B:357-619 [195399]
      Other proteins in same PDB: d3v8wa2, d3v8wb2
      automated match to d1sm2a_
      complexed with 0g2, so4
  14. Domain(s) for 4hct:
  15. Domain(s) for 4hcu:
  16. Domain(s) for 4hcv:
  17. Domain(s) for 4kio:
    1. 2220805Domain d4kioa1: 4kio A:357-619 [224296]
      Other proteins in same PDB: d4kioa2, d4kiob2, d4kioc2, d4kiod2
      automated match to d3miya_
      complexed with g5k, g6k, gol, so4; mutant
    2. 2220806Domain d4kiob1: 4kio B:357-619 [224297]
      Other proteins in same PDB: d4kioa2, d4kiob2, d4kioc2, d4kiod2
      automated match to d3miya_
      complexed with g5k, g6k, gol, so4; mutant
    3. 2220807Domain d4kioc1: 4kio C:357-620 [224298]
      Other proteins in same PDB: d4kioa2, d4kiob2, d4kioc2, d4kiod2
      automated match to d3miya_
      complexed with g5k, g6k, gol, so4; mutant
    4. 2220808Domain d4kiod1: 4kio D:357-618 [224299]
      Other proteins in same PDB: d4kioa2, d4kiob2, d4kioc2, d4kiod2
      automated match to d3miya_
      complexed with g5k, g6k, gol, so4; mutant
  18. Domain(s) for 4l7s:
    1. 2220801Domain d4l7sa1: 4l7s A:357-620 [236195]
      Other proteins in same PDB: d4l7sa2, d4l7sb2
      automated match to d4kioc_
      complexed with g7k, so4; mutant
    2. 2220802Domain d4l7sb1: 4l7s B:357-620 [236196]
      Other proteins in same PDB: d4l7sa2, d4l7sb2
      automated match to d4kioc_
      complexed with g7k, so4; mutant
  19. Domain(s) for 4m0y:
  20. Domain(s) for 4m0z:
  21. Domain(s) for 4m12:
  22. Domain(s) for 4m13:
  23. Domain(s) for 4m14:
  24. Domain(s) for 4m15:
  25. Domain(s) for 4mf0:
    1. 2220823Domain d4mf0a_: 4mf0 A: [228993]
      automated match to d4kioa_
      complexed with 29z
    2. 2220824Domain d4mf0b_: 4mf0 B: [228994]
      automated match to d4kioa_
      complexed with 29z
  26. Domain(s) for 4mf1:
    1. 2220803Domain d4mf1a1: 4mf1 A:357-619 [228995]
      Other proteins in same PDB: d4mf1a2, d4mf1b2
      automated match to d3miya_
      complexed with 29y
    2. 2220804Domain d4mf1b1: 4mf1 B:357-619 [228996]
      Other proteins in same PDB: d4mf1a2, d4mf1b2
      automated match to d3miya_
      complexed with 29y
  27. Domain(s) for 4pp9:
    1. 2220825Domain d4pp9a1: 4pp9 A:357-619 [263560]
      Other proteins in same PDB: d4pp9a2, d4pp9b2
      automated match to d4l7sa_
      complexed with 2vt, so4
    2. 2220826Domain d4pp9b1: 4pp9 B:357-619 [257521]
      Other proteins in same PDB: d4pp9a2, d4pp9b2
      automated match to d4kioc_
      complexed with 2vt, so4
  28. Domain(s) for 4ppa:
    1. 2220829Domain d4ppaa1: 4ppa A:357-619 [267198]
      Other proteins in same PDB: d4ppaa2, d4ppab2
      automated match to d4l7sa_
      complexed with 2vu
    2. 2220830Domain d4ppab1: 4ppa B:357-619 [267199]
      Other proteins in same PDB: d4ppaa2, d4ppab2
      automated match to d4l7sa_
      complexed with 2vu
  29. Domain(s) for 4ppb:
    1. 2220827Domain d4ppba1: 4ppb A:357-619 [267200]
      Other proteins in same PDB: d4ppba2, d4ppbb2
      automated match to d4l7sa_
      complexed with 2vv
    2. 2220828Domain d4ppbb1: 4ppb B:357-619 [267201]
      Other proteins in same PDB: d4ppba2, d4ppbb2
      automated match to d4l7sa_
      complexed with 2vv
  30. Domain(s) for 4ppc:
    1. 2220831Domain d4ppca1: 4ppc A:357-619 [267202]
      Other proteins in same PDB: d4ppca2, d4ppcb2
      automated match to d4l7sa_
      complexed with 2vw
    2. 2220832Domain d4ppcb1: 4ppc B:357-619 [267203]
      Other proteins in same PDB: d4ppca2, d4ppcb2
      automated match to d4l7sa_
      complexed with 2vw
  31. Domain(s) for 4pqn:
  32. Domain(s) for 4qd6:
    1. 2220819Domain d4qd6a1: 4qd6 A:357-619 [268678]
      Other proteins in same PDB: d4qd6a2, d4qd6b2
      automated match to d4l7sa_
      complexed with 30t
    2. 2220820Domain d4qd6b1: 4qd6 B:357-619 [268677]
      Other proteins in same PDB: d4qd6a2, d4qd6b2
      automated match to d4l7sa_
      complexed with 30t
  33. Domain(s) for 4rfm:

More info for Species Human (Homo sapiens) [TaxId:9606] from d.144.1.7 Tyrosine-protein kinase Itk/Tsk

Timeline for Species Human (Homo sapiens) [TaxId:9606] from d.144.1.7 Tyrosine-protein kinase Itk/Tsk: