![]() | Class d: Alpha and beta proteins (a+b) [53931] (396 folds) |
![]() | Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily) consists of two alpha+beta domains, C-terminal domain is mostly alpha helical |
![]() | Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) ![]() shares functional and structural similarities with the ATP-grasp fold and PIPK |
![]() | Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins) members organized in the groups and subfamiles specified by the comments |
![]() | Protein Tyrosine-protein kinase Itk/Tsk [111194] (1 species) PTK group; Tec/Atk subfamily; non-membrane spanning protein tyrosine kinase |
![]() | Species Human (Homo sapiens) [TaxId:9606] [111195] (33 PDB entries) Uniprot Q08881 357-619 |
![]() | Domain d1sm2a_: 1sm2 A: [105754] complexed with stu |
![]() | Domain d1sm2b_: 1sm2 B: [105755] complexed with stu |
![]() | Domain d1snua_: 1snu A: [105829] complexed with stu |
![]() | Domain d1snub_: 1snu B: [105830] complexed with stu |
![]() | Domain d1snxa_: 1snx A: [105831] |
![]() | Domain d1snxb_: 1snx B: [105832] |
![]() | Domain d3miya1: 3miy A:357-619 [181293] Other proteins in same PDB: d3miya2, d3miyb2 automated match to d1sm2a_ complexed with b49 |
![]() | Domain d3miyb1: 3miy B:357-619 [181294] Other proteins in same PDB: d3miya2, d3miyb2 automated match to d1sm2a_ complexed with b49 |
![]() | Domain d3mj1a1: 3mj1 A:357-615 [181296] Other proteins in same PDB: d3mj1a2 automated match to d1sm2a_ complexed with 614 |
![]() | Domain d3mj2a_: 3mj2 A: [181297] automated match to d1sm2a_ complexed with mjg |
![]() | Domain d3qgwa_: 3qgw A: [233325] automated match to d4kioc_ complexed with l7a, pqc |
![]() | Domain d3qgwb_: 3qgw B: [233324] automated match to d4kioc_ complexed with l7a, pqc |
![]() | Domain d3qgya1: 3qgy A:357-618 [233326] Other proteins in same PDB: d3qgya2, d3qgyb2 automated match to d4kioc_ complexed with l7o, pqc |
![]() | Domain d3qgyb1: 3qgy B:357-616 [233327] Other proteins in same PDB: d3qgya2, d3qgyb2 automated match to d4kioc_ complexed with l7o, pqc |
![]() | Domain d3t9ta_: 3t9t A: [185708] automated match to d1sm2a_ complexed with gol, iaq; mutant |
![]() | Domain d3v5ja1: 3v5j A:357-618 [195400] Other proteins in same PDB: d3v5ja2, d3v5jb2 automated match to d1sm2a_ complexed with 0f2, so4 |
![]() | Domain d3v5jb1: 3v5j B:357-620 [201197] Other proteins in same PDB: d3v5ja2, d3v5jb2 automated match to d3v8wb_ complexed with 0f2, so4 |
![]() | Domain d3v5la1: 3v5l A:357-616 [201198] Other proteins in same PDB: d3v5la2, d3v5lb2, d3v5lc2, d3v5ld2 automated match to d3v8wb_ complexed with 0g1, so4 |
![]() | Domain d3v5lb1: 3v5l B:357-619 [195401] Other proteins in same PDB: d3v5la2, d3v5lb2, d3v5lc2, d3v5ld2 automated match to d1sm2a_ complexed with 0g1, so4 |
![]() | Domain d3v5lc1: 3v5l C:357-616 [201199] Other proteins in same PDB: d3v5la2, d3v5lb2, d3v5lc2, d3v5ld2 automated match to d3v8wb_ complexed with 0g1, so4 |
![]() | Domain d3v5ld1: 3v5l D:357-619 [201200] Other proteins in same PDB: d3v5la2, d3v5lb2, d3v5lc2, d3v5ld2 automated match to d3v8wb_ complexed with 0g1, so4 |
![]() | Domain d3v8ta1: 3v8t A:357-618 [217703] Other proteins in same PDB: d3v8ta2, d3v8tb2 automated match to d3v8wb_ complexed with 477, so4 |
![]() | Domain d3v8tb1: 3v8t B:357-619 [217704] Other proteins in same PDB: d3v8ta2, d3v8tb2 automated match to d3v8wb_ complexed with 477, so4 |
![]() | Domain d3v8wa1: 3v8w A:357-619 [201211] Other proteins in same PDB: d3v8wa2, d3v8wb2 automated match to d3v8wb_ complexed with 0g2, so4 |
![]() | Domain d3v8wb1: 3v8w B:357-619 [195399] Other proteins in same PDB: d3v8wa2, d3v8wb2 automated match to d1sm2a_ complexed with 0g2, so4 |
![]() | Domain d4hcta_: 4hct A: [234642] automated match to d4hcua_ complexed with 18r |
![]() | Domain d4hcua_: 4hcu A: [193768] automated match to d1sm2a_ complexed with 13l |
![]() | Domain d4hcva_: 4hcv A: [234641] automated match to d4hcua_ complexed with 13j |
![]() | Domain d4kioa1: 4kio A:357-619 [224296] Other proteins in same PDB: d4kioa2, d4kiob2, d4kioc2, d4kiod2 automated match to d3miya_ complexed with g5k, g6k, gol, so4; mutant |
![]() | Domain d4kiob1: 4kio B:357-619 [224297] Other proteins in same PDB: d4kioa2, d4kiob2, d4kioc2, d4kiod2 automated match to d3miya_ complexed with g5k, g6k, gol, so4; mutant |
![]() | Domain d4kioc1: 4kio C:357-620 [224298] Other proteins in same PDB: d4kioa2, d4kiob2, d4kioc2, d4kiod2 automated match to d3miya_ complexed with g5k, g6k, gol, so4; mutant |
![]() | Domain d4kiod1: 4kio D:357-618 [224299] Other proteins in same PDB: d4kioa2, d4kiob2, d4kioc2, d4kiod2 automated match to d3miya_ complexed with g5k, g6k, gol, so4; mutant |
![]() | Domain d4l7sa1: 4l7s A:357-620 [236195] Other proteins in same PDB: d4l7sa2, d4l7sb2 automated match to d4kioc_ complexed with g7k, so4; mutant |
![]() | Domain d4l7sb1: 4l7s B:357-620 [236196] Other proteins in same PDB: d4l7sa2, d4l7sb2 automated match to d4kioc_ complexed with g7k, so4; mutant |
![]() | Domain d4m0ya_: 4m0y A: [238191] automated match to d4hcua_ complexed with m0y |
![]() | Domain d4m0za_: 4m0z A: [238190] automated match to d4hcta_ complexed with m0z |
![]() | Domain d4m12a_: 4m12 A: [238189] automated match to d4hcta_ complexed with 1yz |
![]() | Domain d4m13a_: 4m13 A: [238188] automated match to d4hcta_ complexed with 1e0 |
![]() | Domain d4m14a_: 4m14 A: [238187] automated match to d4hcta_ complexed with qws |
![]() | Domain d4m15a_: 4m15 A: [238192] automated match to d4hcta_ complexed with adp, qws |
![]() | Domain d4mf0a_: 4mf0 A: [228993] automated match to d4kioa_ complexed with 29z |
![]() | Domain d4mf0b_: 4mf0 B: [228994] automated match to d4kioa_ complexed with 29z |
![]() | Domain d4mf1a1: 4mf1 A:357-619 [228995] Other proteins in same PDB: d4mf1a2, d4mf1b2 automated match to d3miya_ complexed with 29y |
![]() | Domain d4mf1b1: 4mf1 B:357-619 [228996] Other proteins in same PDB: d4mf1a2, d4mf1b2 automated match to d3miya_ complexed with 29y |
![]() | Domain d4pp9a1: 4pp9 A:357-619 [263560] Other proteins in same PDB: d4pp9a2, d4pp9b2 automated match to d4l7sa_ complexed with 2vt, so4 |
![]() | Domain d4pp9b1: 4pp9 B:357-619 [257521] Other proteins in same PDB: d4pp9a2, d4pp9b2 automated match to d4kioc_ complexed with 2vt, so4 |
![]() | Domain d4ppaa1: 4ppa A:357-619 [267198] Other proteins in same PDB: d4ppaa2, d4ppab2 automated match to d4l7sa_ complexed with 2vu |
![]() | Domain d4ppab1: 4ppa B:357-619 [267199] Other proteins in same PDB: d4ppaa2, d4ppab2 automated match to d4l7sa_ complexed with 2vu |
![]() | Domain d4ppba1: 4ppb A:357-619 [267200] Other proteins in same PDB: d4ppba2, d4ppbb2 automated match to d4l7sa_ complexed with 2vv |
![]() | Domain d4ppbb1: 4ppb B:357-619 [267201] Other proteins in same PDB: d4ppba2, d4ppbb2 automated match to d4l7sa_ complexed with 2vv |
![]() | Domain d4ppca1: 4ppc A:357-619 [267202] Other proteins in same PDB: d4ppca2, d4ppcb2 automated match to d4l7sa_ complexed with 2vw |
![]() | Domain d4ppcb1: 4ppc B:357-619 [267203] Other proteins in same PDB: d4ppca2, d4ppcb2 automated match to d4l7sa_ complexed with 2vw |
![]() | Domain d4pqna_: 4pqn A: [258232] automated match to d3v5jb_ complexed with 2w6, p4g |
![]() | Domain d4qd6a1: 4qd6 A:357-619 [268678] Other proteins in same PDB: d4qd6a2, d4qd6b2 automated match to d4l7sa_ complexed with 30t |
![]() | Domain d4qd6b1: 4qd6 B:357-619 [268677] Other proteins in same PDB: d4qd6a2, d4qd6b2 automated match to d4l7sa_ complexed with 30t |
![]() | Domain d4rfma1: 4rfm A:357-618 [271977] Other proteins in same PDB: d4rfma2 automated match to d3v5jb_ complexed with 3p6 |
Timeline for Species Human (Homo sapiens) [TaxId:9606] from d.144.1.7 Tyrosine-protein kinase Itk/Tsk: