SCOPe 2.08: Superfamily d.278.1: Ligand-binding domain in the NO signalling and Golgi transport

Lineage for Superfamily d.278.1: Ligand-binding domain in the NO signalling and Golgi transport

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.278: Ligand-binding domain in the NO signalling and Golgi transport [111125] (1 superfamily)
   an N-terminal helical bundle and the C-terminal alpha-beta(2)-alpha-beta(2) subdomain enclose a ligand-binding cavity

4. Superfamily d.278.1: Ligand-binding domain in the NO signalling and Golgi transport [111126] (4 families)

Families:

1. d.278.1.1: H-NOX domain [111127] (2 proteins)
   binds heme between the N-terminal 4-helical bundle and the C-terminal alpha-beta(2)-alpha-beta(2) subdomains
   automatically mapped to Pfam PF07700

2. d.278.1.2: TRAPP components [118076] (3 proteins)
   Pfam PF04051; form homo- and hetero-dimers with the first two helices of one subunit complementing the fold of the other subunit to the H-NOX domain fold

3. d.278.1.3: MJ1460-like [160689] (1 protein)
   C-terminal part corresponds to Pfam PF02830; V4R (vinyl 4 reductase) domain

4. d.278.1.0: automated matches [338427] (1 protein)
   not a true family

More info for Superfamily d.278.1: Ligand-binding domain in the NO signalling and Golgi transport

Timeline for Superfamily d.278.1: Ligand-binding domain in the NO signalling and Golgi transport:

• Superfamily d.278.1: Ligand-binding domain in the NO signalling and Golgi transport first appeared in SCOP 1.69, called Superfamily d.278.1: H-NOX domain
  
• Superfamily d.278.1: Ligand-binding domain in the NO signalling and Golgi transport appears in SCOPe 2.07