SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for Species: Mouse (Mus musculus) [TaxId: 10090]

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2155547Fold d.4: His-Me finger endonucleases [54059] (1 superfamily)
    core: (alpha)-beta-omega_loop-beta-alpha; embeded in larger different structures
  4. 2155548Superfamily d.4.1: His-Me finger endonucleases [54060] (7 families) (S)
    common motif contains conserved histidine residue and metal-binding site
  5. 2155686Family d.4.1.7: Caspase-activated DNase, CAD (DffB, DFF40) [110778] (1 protein)
  6. 2155687Protein Caspase-activated DNase, CAD (DffB, DFF40) [110779] (1 species)
  7. 2155688Species Mouse (Mus musculus) [TaxId:10090] [110780] (1 PDB entry)
    Uniprot O54788 85-329 # structure of the N-terminal, CAD domain (1-87) is solved separately; (54282)

PDB entry in Species: Mouse (Mus musculus) [TaxId: 10090]:

More info for Species Mouse (Mus musculus) [TaxId:10090] from d.4.1.7 Caspase-activated DNase, CAD (DffB, DFF40)

Timeline for Species Mouse (Mus musculus) [TaxId:10090] from d.4.1.7 Caspase-activated DNase, CAD (DffB, DFF40):