SCOPe 2.08: Family d.3.1.11: Ubiquitin thiolesterase protein OTUB2 (Otubain-2)

Lineage for Family d.3.1.11: Ubiquitin thiolesterase protein OTUB2 (Otubain-2)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.3: Cysteine proteinases [54000] (1 superfamily)
   consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn

4. Superfamily d.3.1: Cysteine proteinases [54001] (24 families)
   the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet

5. Family d.3.1.11: Ubiquitin thiolesterase protein OTUB2 (Otubain-2) [110773] (2 proteins)
   probably the same as Pfam PF02338, OTU-like cysteine protease, but 1TFF (Uniprot Q96DC9) was not detected by the Pfam model

Proteins:

1. Ubiquitin thiolesterase protein OTUB2 (Otubain-2) [110774] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [110775] (1 PDB entry)
     Uniprot Q96DC9

2. automated matches [197305] (1 species)
   not a true protein

   • Species Human (Homo sapiens) [TaxId:9606] [197306] (13 PDB entries)

More info for Family d.3.1.11: Ubiquitin thiolesterase protein OTUB2 (Otubain-2)

Timeline for Family d.3.1.11: Ubiquitin thiolesterase protein OTUB2 (Otubain-2):

• Family d.3.1.11: Ubiquitin thiolesterase protein OTUB2 (Otubain-2) first appeared in SCOP 1.69
  
• Family d.3.1.11: Ubiquitin thiolesterase protein OTUB2 (Otubain-2) appears in SCOPe 2.07