Lineage for Protein: 3-hydroxy-3-methylglutaryl CoA synthase MvaS

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2488301Fold c.95: Thiolase-like [53900] (1 superfamily)
    consists of two similar domains related by pseudo dyad; duplication
    3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32451; strand 5 is antiparallel to the rest
  4. 2488302Superfamily c.95.1: Thiolase-like [53901] (3 families) (S)
  5. 2488780Family c.95.1.2: Chalcone synthase-like [53914] (9 proteins)
  6. 2488781Protein 3-hydroxy-3-methylglutaryl CoA synthase MvaS [110760] (2 species)
    most similar to FabH

Species:

  1. 2488782Enterococcus faecalis [TaxId:1351] [225034] (4 PDB entries)
    1. Domains for 1x9e:
      1. 2488803Domain d1x9ea1: 1x9e A:1-167 [203077]
        automated match to d1tvza1
        complexed with so4
      2. 2488804Domain d1x9ea2: 1x9e A:168-383 [203078]
        automated match to d1xpma2
        complexed with so4
      3. 2488805Domain d1x9eb1: 1x9e B:1-167 [203079]
        automated match to d1tvza1
        complexed with so4
      4. 2488806Domain d1x9eb2: 1x9e B:168-383 [203080]
        automated match to d1xpma2
        complexed with so4
    2. Domains for 2hdb:
      1. 2488791Domain d2hdba1: 2hdb A:1-167 [204540]
        automated match to d1tvza1
        complexed with mes, so4; mutant
      2. 2488792Domain d2hdba2: 2hdb A:168-383 [204541]
        automated match to d1xpma2
        complexed with mes, so4; mutant
      3. 2488793Domain d2hdbb1: 2hdb B:1-167 [204542]
        automated match to d1tvza1
        complexed with mes, so4; mutant
      4. 2488794Domain d2hdbb2: 2hdb B:168-383 [204543]
        automated match to d1xpma2
        complexed with mes, so4; mutant
    3. Domains for 3v4n:
      1. 2488783Domain d3v4na1: 3v4n A:1-167 [217639]
        Other proteins in same PDB: d3v4na3, d3v4nb3
        automated match to d1tvza1
        complexed with btb
      2. 2488784Domain d3v4na2: 3v4n A:168-383 [217640]
        Other proteins in same PDB: d3v4na3, d3v4nb3
        automated match to d1xpma2
        complexed with btb
      3. 2488785Domain d3v4nb1: 3v4n B:1-167 [217641]
        Other proteins in same PDB: d3v4na3, d3v4nb3
        automated match to d1tvza1
        complexed with btb
      4. 2488786Domain d3v4nb2: 3v4n B:168-383 [217642]
        Other proteins in same PDB: d3v4na3, d3v4nb3
        automated match to d1xpma2
        complexed with btb
      5. 2488787Domain d3v4nc1: 3v4n C:1-167 [217643]
        Other proteins in same PDB: d3v4na3, d3v4nb3
        automated match to d1tvza1
        complexed with btb
      6. 2488788Domain d3v4nc2: 3v4n C:168-383 [217644]
        Other proteins in same PDB: d3v4na3, d3v4nb3
        automated match to d1xpma2
        complexed with btb
      7. 2488789Domain d3v4nd1: 3v4n D:1-167 [217645]
        Other proteins in same PDB: d3v4na3, d3v4nb3
        automated match to d1tvza1
        complexed with btb
      8. 2488790Domain d3v4nd2: 3v4n D:168-383 [217646]
        Other proteins in same PDB: d3v4na3, d3v4nb3
        automated match to d1xpma2
        complexed with btb
    4. Domains for 3v4x:
      1. 2488795Domain d3v4xa1: 3v4x A:1-167 [217655]
        Other proteins in same PDB: d3v4xa3, d3v4xb3, d3v4xc3, d3v4xd3
        automated match to d1tvza1
        complexed with f24
      2. 2488796Domain d3v4xa2: 3v4x A:168-383 [217656]
        Other proteins in same PDB: d3v4xa3, d3v4xb3, d3v4xc3, d3v4xd3
        automated match to d1xpma2
        complexed with f24
      3. 2488797Domain d3v4xb1: 3v4x B:1-167 [217657]
        Other proteins in same PDB: d3v4xa3, d3v4xb3, d3v4xc3, d3v4xd3
        automated match to d1tvza1
        complexed with f24
      4. 2488798Domain d3v4xb2: 3v4x B:168-383 [217658]
        Other proteins in same PDB: d3v4xa3, d3v4xb3, d3v4xc3, d3v4xd3
        automated match to d1xpma2
        complexed with f24
      5. 2488799Domain d3v4xc1: 3v4x C:1-167 [217659]
        Other proteins in same PDB: d3v4xa3, d3v4xb3, d3v4xc3, d3v4xd3
        automated match to d1tvza1
        complexed with f24
      6. 2488800Domain d3v4xc2: 3v4x C:168-383 [217660]
        Other proteins in same PDB: d3v4xa3, d3v4xb3, d3v4xc3, d3v4xd3
        automated match to d1xpma2
        complexed with f24
      7. 2488801Domain d3v4xd1: 3v4x D:1-167 [217661]
        Other proteins in same PDB: d3v4xa3, d3v4xb3, d3v4xc3, d3v4xd3
        automated match to d1tvza1
        complexed with f24
      8. 2488802Domain d3v4xd2: 3v4x D:168-383 [217662]
        Other proteins in same PDB: d3v4xa3, d3v4xb3, d3v4xc3, d3v4xd3
        automated match to d1xpma2
        complexed with f24
  2. 2488807Staphylococcus aureus [TaxId:1280] [110761] (5 PDB entries)
    Uniprot Q7A3F6
    1. Domains for 1tvz:
      1. 2488808Domain d1tvza1: 1tvz A:2-167 [107367]
        complexed with so4
      2. 2488809Domain d1tvza2: 1tvz A:168-388 [107368]
        complexed with so4
    2. Domains for 1txt:
      1. 2488818Domain d1txta1: 1txt A:2-167 [107431]
        complexed with caa
      2. 2488819Domain d1txta2: 1txt A:168-388 [107432]
        complexed with caa
      3. 2488820Domain d1txtb1: 1txt B:2-167 [107433]
        complexed with caa
      4. 2488821Domain d1txtb2: 1txt B:168-388 [107434]
        complexed with caa
      5. 2488822Domain d1txtc1: 1txt C:2-167 [107435]
        complexed with caa
      6. 2488823Domain d1txtc2: 1txt C:168-388 [107436]
        complexed with caa
      7. 2488824Domain d1txtd1: 1txt D:2-167 [107437]
        complexed with caa
      8. 2488825Domain d1txtd2: 1txt D:168-388 [107438]
        complexed with caa
    3. Domains for 1xpk:
      1. 2488834Domain d1xpka1: 1xpk A:2-167 [115743]
        complexed with caa, hmg, so4
      2. 2488835Domain d1xpka2: 1xpk A:168-388 [115744]
        complexed with caa, hmg, so4
      3. 2488836Domain d1xpkb1: 1xpk B:2-167 [115745]
        complexed with caa, hmg, so4
      4. 2488837Domain d1xpkb2: 1xpk B:168-388 [115746]
        complexed with caa, hmg, so4
      5. 2488838Domain d1xpkc1: 1xpk C:2-167 [115747]
        complexed with caa, hmg, so4
      6. 2488839Domain d1xpkc2: 1xpk C:168-388 [115748]
        complexed with caa, hmg, so4
      7. 2488840Domain d1xpkd1: 1xpk D:2-167 [115749]
        complexed with caa, hmg, so4
      8. 2488841Domain d1xpkd2: 1xpk D:168-388 [115750]
        complexed with caa, hmg, so4
    4. Domains for 1xpl:
      1. 2488826Domain d1xpla1: 1xpl A:3-167 [115751]
        Other proteins in same PDB: d1xpla3, d1xpla4, d1xplb3, d1xplb4, d1xplc3, d1xplc4, d1xpld3, d1xpld4
        complexed with caa, so4
      2. 2488827Domain d1xpla2: 1xpl A:168-388 [115752]
        Other proteins in same PDB: d1xpla3, d1xpla4, d1xplb3, d1xplb4, d1xplc3, d1xplc4, d1xpld3, d1xpld4
        complexed with caa, so4
      3. 2488828Domain d1xplb1: 1xpl B:3-167 [115753]
        Other proteins in same PDB: d1xpla3, d1xpla4, d1xplb3, d1xplb4, d1xplc3, d1xplc4, d1xpld3, d1xpld4
        complexed with caa, so4
      4. 2488829Domain d1xplb2: 1xpl B:168-388 [115754]
        Other proteins in same PDB: d1xpla3, d1xpla4, d1xplb3, d1xplb4, d1xplc3, d1xplc4, d1xpld3, d1xpld4
        complexed with caa, so4
      5. 2488830Domain d1xplc1: 1xpl C:3-167 [115755]
        Other proteins in same PDB: d1xpla3, d1xpla4, d1xplb3, d1xplb4, d1xplc3, d1xplc4, d1xpld3, d1xpld4
        complexed with caa, so4
      6. 2488831Domain d1xplc2: 1xpl C:168-388 [115756]
        Other proteins in same PDB: d1xpla3, d1xpla4, d1xplb3, d1xplb4, d1xplc3, d1xplc4, d1xpld3, d1xpld4
        complexed with caa, so4
      7. 2488832Domain d1xpld1: 1xpl D:3-167 [115757]
        Other proteins in same PDB: d1xpla3, d1xpla4, d1xplb3, d1xplb4, d1xplc3, d1xplc4, d1xpld3, d1xpld4
        complexed with caa, so4
      8. 2488833Domain d1xpld2: 1xpl D:168-388 [115758]
        Other proteins in same PDB: d1xpla3, d1xpla4, d1xplb3, d1xplb4, d1xplc3, d1xplc4, d1xpld3, d1xpld4
        complexed with caa, so4
    5. Domains for 1xpm:
      1. 2488810Domain d1xpma1: 1xpm A:3-167 [115759]
        Other proteins in same PDB: d1xpma3, d1xpma4, d1xpmb3, d1xpmb4, d1xpmc3, d1xpmc4, d1xpmd3, d1xpmd4
        complexed with caa, hmg, so4
      2. 2488811Domain d1xpma2: 1xpm A:168-388 [115760]
        Other proteins in same PDB: d1xpma3, d1xpma4, d1xpmb3, d1xpmb4, d1xpmc3, d1xpmc4, d1xpmd3, d1xpmd4
        complexed with caa, hmg, so4
      3. 2488812Domain d1xpmb1: 1xpm B:3-167 [115761]
        Other proteins in same PDB: d1xpma3, d1xpma4, d1xpmb3, d1xpmb4, d1xpmc3, d1xpmc4, d1xpmd3, d1xpmd4
        complexed with caa, hmg, so4
      4. 2488813Domain d1xpmb2: 1xpm B:168-388 [115762]
        Other proteins in same PDB: d1xpma3, d1xpma4, d1xpmb3, d1xpmb4, d1xpmc3, d1xpmc4, d1xpmd3, d1xpmd4
        complexed with caa, hmg, so4
      5. 2488814Domain d1xpmc1: 1xpm C:3-167 [115763]
        Other proteins in same PDB: d1xpma3, d1xpma4, d1xpmb3, d1xpmb4, d1xpmc3, d1xpmc4, d1xpmd3, d1xpmd4
        complexed with caa, hmg, so4
      6. 2488815Domain d1xpmc2: 1xpm C:168-388 [115764]
        Other proteins in same PDB: d1xpma3, d1xpma4, d1xpmb3, d1xpmb4, d1xpmc3, d1xpmc4, d1xpmd3, d1xpmd4
        complexed with caa, hmg, so4
      7. 2488816Domain d1xpmd1: 1xpm D:3-167 [115765]
        Other proteins in same PDB: d1xpma3, d1xpma4, d1xpmb3, d1xpmb4, d1xpmc3, d1xpmc4, d1xpmd3, d1xpmd4
        complexed with caa, hmg, so4
      8. 2488817Domain d1xpmd2: 1xpm D:168-388 [115766]
        Other proteins in same PDB: d1xpma3, d1xpma4, d1xpmb3, d1xpmb4, d1xpmc3, d1xpmc4, d1xpmd3, d1xpmd4
        complexed with caa, hmg, so4

More info for Protein 3-hydroxy-3-methylglutaryl CoA synthase MvaS from c.95.1.2: Chalcone synthase-like

Timeline for Protein 3-hydroxy-3-methylglutaryl CoA synthase MvaS from c.95.1.2: Chalcone synthase-like: