Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOP 1.75
  2. 814173Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 843892Fold c.77: Isocitrate/Isopropylmalate dehydrogenase-like [53658] (1 superfamily)
    consists of two intertwined (sub)domains related by pseudo dyad; duplication
    3 layers: a/b/a; single mixed beta-sheet of 10 strands, order 213A945867 (A=10); strands from 5 to 9 are antiparallel to the rest
  4. 843893Superfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenase-like [53659] (5 families) (S)
    the constituent families form similar dimers
  5. 843894Family c.77.1.1: Dimeric isocitrate & isopropylmalate dehydrogenases [53660] (3 proteins)
    the active site is between the two identical subunits
  6. 843981Protein NADP-dependent isocitrate dehydrogenase [82524] (2 species)
  7. 843982Species Human (Homo sapiens) [TaxId:9606] [110715] (2 PDB entries)
    Uniprot O75874

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

  1. Domain(s) for 1t09:
    1. 843987Domain d1t09a_: 1t09 A: [106197]
    2. 843988Domain d1t09b_: 1t09 B: [106198]
      complexed with nap
  2. Domain(s) for 1t0l:
    1. 843983Domain d1t0la_: 1t0l A: [106216]
    2. 843984Domain d1t0lb_: 1t0l B: [106217]
    3. 843985Domain d1t0lc_: 1t0l C: [106218]
    4. 843986Domain d1t0ld_: 1t0l D: [106219]
      complexed with ca, ict, nap

More info for Species Human (Homo sapiens) [TaxId:9606] from c.77.1.1 NADP-dependent isocitrate dehydrogenase

Timeline for Species Human (Homo sapiens) [TaxId:9606] from c.77.1.1 NADP-dependent isocitrate dehydrogenase: