SCOPe 2.08: Family c.124.1.6: Methenyltetrahydrofolate synthetase

Lineage for Family c.124.1.6: Methenyltetrahydrofolate synthetase

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.124: NagB/RpiA/CoA transferase-like [100949] (1 superfamily)
   core: 3 layers: a/b/a; parallel or mixed beta-sheet of 6 strands, order 321456

4. Superfamily c.124.1: NagB/RpiA/CoA transferase-like [100950] (9 families)

5. Family c.124.1.6: Methenyltetrahydrofolate synthetase [110520] (3 proteins)
   Pfam PF01812; 5-FTHF cyclo-ligase

Proteins:

1. 5,10-methenyltetrahydrofolate synthetase homolog MPN348 [110523] (1 species)

   • Species Mycoplasma pneumoniae [TaxId:2104] [110524] (3 PDB entries)
     Uniprot P75430

2. Hypothetical protein aq_1731 [110521] (1 species)

   • Species Aquifex aeolicus [TaxId:63363] [110522] (1 PDB entry)
     Uniprot O67621

3. Hypothetical protein TTHA1611 [117519] (1 species)

   • Species Thermus thermophilus [TaxId:274] [117520] (1 PDB entry)
     Uniprot Q5SHW9 1-175

More info for Family c.124.1.6: Methenyltetrahydrofolate synthetase

Timeline for Family c.124.1.6: Methenyltetrahydrofolate synthetase:

• Family c.124.1.6: Methenyltetrahydrofolate synthetase first appeared in SCOP 1.69, called Family c.124.1.6: Methenyltetrahydrofolate synthetase (5-FTHF cyclo-ligase; Pfam 01812)
  
• Family c.124.1.6: Methenyltetrahydrofolate synthetase appears in SCOPe 2.07