SCOPe 2.06: Protein: 2-isopropylmalate synthase LeuA, catalytic domain

Lineage for Protein: 2-isopropylmalate synthase LeuA, catalytic domain

Root: SCOPe 2.06
Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
the first seven superfamilies have similar phosphate-binding sites

Superfamily c.1.10: Aldolase [51569] (9 families)
Common fold covers whole protein structure
Family c.1.10.5: HMGL-like [89494] (3 proteins)
Pfam PF00682
Protein 2-isopropylmalate synthase LeuA, catalytic domain [110364] (1 species)

Species:

Mycobacterium tuberculosis [TaxId:1773] [110365] (1 PDB entry)
Uniprot P96420
- Domains for 1sr9:
  1. Domain d1sr9a2: 1sr9 A:61-370 [105961]
    Other proteins in same PDB: d1sr9a1, d1sr9a3, d1sr9b1, d1sr9b3
    complexed with cl, kiv, zn
  2. Domain d1sr9b2: 1sr9 B:61-370 [105964]
    Other proteins in same PDB: d1sr9a1, d1sr9a3, d1sr9b1, d1sr9b3
    complexed with cl, kiv, zn

More info for Protein 2-isopropylmalate synthase LeuA, catalytic domain from c.1.10.5: HMGL-like

Timeline for Protein 2-isopropylmalate synthase LeuA, catalytic domain from c.1.10.5: HMGL-like:

Protein 2-isopropylmalate synthase LeuA, catalytic domain from c.1.10.5: HMGL-like first appeared in SCOP 1.69, called Protein 2-isopropylmalate synthase LeuA, catalytic domain from c.1.10.5: HMGL-like (Pfam 00682)
Protein 2-isopropylmalate synthase LeuA, catalytic domain from c.1.10.5: HMGL-like appears in SCOPe 2.05
Protein 2-isopropylmalate synthase LeuA, catalytic domain from c.1.10.5: HMGL-like appears in SCOPe 2.07
Protein 2-isopropylmalate synthase LeuA, catalytic domain from c.1.10.5: HMGL-like appears in the current release, SCOPe 2.08