SCOP 1.69: Family a.216.1.1: I/LWEQ domain (Pfam 01608)

Lineage for Family a.216.1.1: I/LWEQ domain (Pfam 01608)

1. Root: SCOP 1.69

2. Class a: All alpha proteins [46456] (218 folds)

3. Fold a.216: I/LWEQ domain (Pfam 01608) [109884] (1 superfamily)
   5 helices; bundle, closed, left-handed twist

4. Superfamily a.216.1: I/LWEQ domain (Pfam 01608) [109885] (1 family)

5. Family a.216.1.1: I/LWEQ domain (Pfam 01608) [109886] (2 proteins)
   actin-binding motif that adopts different folds; possibly refolds upon binding

Proteins:

1. Huntingtin interacting protein 12 [109887] (1 species)
   Hip1r thatch domain core

   • Species Human (Homo sapiens) [TaxId:9606] [109888] (1 PDB entry)

2. Talin 1 [109889] (1 species)
   4-helical bundle of the Bromodomain-like fold (scop_cf 47363); similar to helices 2-5 of the Huntingtin interacting protein 12

   • Species Mouse (Mus musculus) [TaxId:10090] [109890] (1 PDB entry)

More info for Family a.216.1.1: I/LWEQ domain (Pfam 01608)

Timeline for Family a.216.1.1: I/LWEQ domain (Pfam 01608):

• Family a.216.1.1: I/LWEQ domain (Pfam 01608) is new in SCOP 1.69
  
• Family a.216.1.1: I/LWEQ domain (Pfam 01608) is called Family a.216.1.1: I/LWEQ domain in SCOP 1.71
  
• Family a.216.1.1: I/LWEQ domain (Pfam 01608) appears in the current release, SCOPe 2.08, called Family a.216.1.1: I/LWEQ domain