SCOPe 2.07: Protein: 20alpha-hydroxysteroid dehydrogenase

Lineage for Protein: 20alpha-hydroxysteroid dehydrogenase

Root: SCOPe 2.07
Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
the first seven superfamilies have similar phosphate-binding sites

Superfamily c.1.7: NAD(P)-linked oxidoreductase [51430] (2 families)
Family c.1.7.1: Aldo-keto reductases (NADP) [51431] (16 proteins)
Common fold covers whole protein structure
Protein 20alpha-hydroxysteroid dehydrogenase [109609] (2 species)

Species:

Human (Homo sapiens) [TaxId:9606] [109610] (1 PDB entry)
- Domain for 1mrq:
  - Domain d1mrqa1: 1mrq A:2-323 [91445]
    Other proteins in same PDB: d1mrqa2
    complexed with bme, nap, str
Rabbit (Oryctolagus cuniculus) [TaxId:9986] [110348] (2 PDB entries)
Uniprot P80508
1. Domains for 1q13:
  1. Domain d1q13a_: 1q13 A: [111648]
    complexed with nap, so4, tes
  2. Domain d1q13b_: 1q13 B: [111649]
    complexed with nap, so4, tes
2. Domains for 1q5m:
  1. Domain d1q5ma_: 1q5m A: [104539]
    complexed with ndp, so4
  2. Domain d1q5mb_: 1q5m B: [104540]
    complexed with ndp, so4

More info for Protein 20alpha-hydroxysteroid dehydrogenase from c.1.7.1: Aldo-keto reductases (NADP)

Timeline for Protein 20alpha-hydroxysteroid dehydrogenase from c.1.7.1: Aldo-keto reductases (NADP):

Protein 20alpha-hydroxysteroid dehydrogenase from c.1.7.1: Aldo-keto reductases (NADP) first appeared in SCOP 1.69
Protein 20alpha-hydroxysteroid dehydrogenase from c.1.7.1: Aldo-keto reductases (NADP) appears in SCOPe 2.06
Protein 20alpha-hydroxysteroid dehydrogenase from c.1.7.1: Aldo-keto reductases (NADP) appears in the current release, SCOPe 2.08