Class b: All beta proteins [48724] (177 folds) |
Fold b.55: PH domain-like barrel [50728] (2 superfamilies) barrel, partly opened; n*=6, S*=12; meander; capped by an alpha-helix |
Superfamily b.55.1: PH domain-like [50729] (14 families) |
Family b.55.1.1: Pleckstrin-homology domain (PH domain) [50730] (48 proteins) Pfam PF00169 |
Protein Rho guanine nucleotide exchange factor 12 [110270] (1 species) |
Species Human (Homo sapiens), gamma isoform [TaxId:9606] [110271] (2 PDB entries) Uniprot Q9NZN5 766-1138 |
Domain d1x86g2: 1x86 G:1020-1133 [109514] Other proteins in same PDB: d1x86a1, d1x86b_, d1x86c1, d1x86d_, d1x86e1, d1x86f_, d1x86g1, d1x86h_ complexed with po4 |
PDB Entry: 1x86 (more details), 3.22 Å
SCOPe Domain Sequences for d1x86g2:
Sequence, based on SEQRES records: (download)
>d1x86g2 b.55.1.1 (G:1020-1133) Rho guanine nucleotide exchange factor 12 {Human (Homo sapiens), gamma isoform [TaxId: 9606]} mihegplvwkvnrdktidlytllledilvllqkqddrlvlrchskilastadskhtfspv iklstvlvrqvatdnkalfvismsdngaqiyelvaqtvsektvwqdlicrmaas
>d1x86g2 b.55.1.1 (G:1020-1133) Rho guanine nucleotide exchange factor 12 {Human (Homo sapiens), gamma isoform [TaxId: 9606]} mihegplvwdlytllledilvllqkqddrlvviklstvlvrqvatdnkalfvisqiyelv aqtvsektvwqdlicrmaas
Timeline for d1x86g2: