SCOPe 2.03: Domain d1w0fa_: 1w0f A:

Lineage for d1w0fa_ (1w0f A:)

1. Root: SCOPe 2.03

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.104: Cytochrome P450 [48263] (1 superfamily)
   multihelical

4. Superfamily a.104.1: Cytochrome P450 [48264] (2 families)

5. Family a.104.1.1: Cytochrome P450 [48265] (23 proteins)

6. Protein Mammalian cytochrome P450 3a4 [109958] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [109959] (6 PDB entries)
   Uniprot P08684

8. Domain d1w0fa_: 1w0f A: [108987]
   complexed with hem, str

Details for d1w0fa_

PDB Entry: 1w0f, 2.65 Å

PDB Description: crystal structure of human cytochrome p450 3a4

PDB Compounds: (A:) cytochrome p450 3a4

SCOPe Domain Sequences for d1w0fa_:

Sequence, based on SEQRES records:

>d1w0fa_ a.104.1.1 (A:) Mammalian cytochrome P450 3a4 {Human (Homo sapiens) [TaxId: 9606]}
ygthshglfkklgipgptplpflgnilsyhkgfcmfdmechkkygkvwgfydgqqpvlai
tdpdmiktvlvkecysvftnrrpfgpvgfmksaisiaedeewkrlrsllsptftsgklke
mvpiiaqygdvlvrnlrreaetgkpvtlkdvfgaysmdvitstsfgvnidslnnpqdpfv
entkkllrfdfldpfflsitvfpflipilevlnicvfprevtnflrksvkrmkesrledt
qkhrvdflqlmidsqnsketeshkalsdlelvaqsiififagyettssvlsfimyelath
pdvqqklqeeidavlpnkapptydtvlqmeyldmvvnetlrlfpiamrlervckkdvein
gmfipkgvvvmipsyalhrdpkywtepekflperfskknkdnidpyiytpfgsgprncig
mrfalmnmklalirvlqnfsfkpcketqiplklslggllqpekpvvlkvesrdg

Sequence, based on observed residues (ATOM records):

>d1w0fa_ a.104.1.1 (A:) Mammalian cytochrome P450 3a4 {Human (Homo sapiens) [TaxId: 9606]}
ygthshglfkklgipgptplpflgnilsyhkgfcmfdmechkkygkvwgfydgqqpvlai
tdpdmiktvlvkecysvftnrrpfgpvgfmksaisiaedeewkrlrsllsptftsgklke
mvpiiaqygdvlvrnlrreaetgkpvtlkdvfgaysmdvitstsfgvnidslnnpqdpfv
entkkllrfdfldpfflsitvfpflipilevlnicvfprevtnflrksvkrmkesrlvdf
lqlmidsqnalsdlelvaqsiififagyettssvlsfimyelathpdvqqklqeeidavl
pnkapptydtvlqmeyldmvvnetlrlfpiamrlervckkdveingmfipkgvvvmipsy
alhrdpkywtepekflperfskknkdnidpyiytpfgsgprncigmrfalmnmklalirv
lqnfsfkpcketqiplklslggllqpekpvvlkvesrdg

Timeline for d1w0fa_:

• d1w0fa_ first appeared in SCOP 1.69
  
• d1w0fa_ appears in SCOPe 2.02
  
• d1w0fa_ appears in SCOPe 2.04
  
• d1w0fa_ appears in the current release, SCOPe 2.08