Lineage for d1w0ea_ (1w0e A:)

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 2004931Fold a.104: Cytochrome P450 [48263] (1 superfamily)
    multihelical
  4. 2004932Superfamily a.104.1: Cytochrome P450 [48264] (2 families) (S)
  5. 2004933Family a.104.1.1: Cytochrome P450 [48265] (23 protein domains)
  6. 2005397Protein Mammalian cytochrome P450 3a4 [109958] (1 species)
  7. 2005398Species Human (Homo sapiens) [TaxId:9606] [109959] (7 PDB entries)
    Uniprot P08684
  8. 2005412Domain d1w0ea_: 1w0e A: [108986]
    complexed with hem

Details for d1w0ea_

PDB Entry: 1w0e (more details), 2.8 Å

PDB Description: crystal structure of human cytochrome p450 3a4
PDB Compounds: (A:) cytochrome p450 3a4

SCOPe Domain Sequences for d1w0ea_:

Sequence, based on SEQRES records: (download)

>d1w0ea_ a.104.1.1 (A:) Mammalian cytochrome P450 3a4 {Human (Homo sapiens) [TaxId: 9606]}
ygthshglfkklgipgptplpflgnilsyhkgfcmfdmechkkygkvwgfydgqqpvlai
tdpdmiktvlvkecysvftnrrpfgpvgfmksaisiaedeewkrlrsllsptftsgklke
mvpiiaqygdvlvrnlrreaetgkpvtlkdvfgaysmdvitstsfgvnidslnnpqdpfv
entkkllrfdfldpfflsitvfpflipilevlnicvfprevtnflrksvkrmkesrledt
qkhrvdflqlmidsqnsketeshkalsdlelvaqsiififagyettssvlsfimyelath
pdvqqklqeeidavlpnkapptydtvlqmeyldmvvnetlrlfpiamrlervckkdvein
gmfipkgvvvmipsyalhrdpkywtepekflperfskknkdnidpyiytpfgsgprncig
mrfalmnmklalirvlqnfsfkpcketqiplklslggllqpekpvvlkvesrdgt

Sequence, based on observed residues (ATOM records): (download)

>d1w0ea_ a.104.1.1 (A:) Mammalian cytochrome P450 3a4 {Human (Homo sapiens) [TaxId: 9606]}
ygthshglfkklgipgptplpflgnilsyhkgfcmfdmechkkygkvwgfydgqqpvlai
tdpdmiktvlvkecysvftnrrpfgpvgfmksaisiaedeewkrlrsllsptftsgklke
mvpiiaqygdvlvrnlrreaetgkpvtlkdvfgaysmdvitstsfgvnidslnnpqdpfv
entkkllrfdfldpfflsitvfpflipilevlnicvfprevtnflrksvkrmkesrlflq
lmidsdlelvaqsiififagyettssvlsfimyelathpdvqqklqeeidavlpnkappt
ydtvlqmeyldmvvnetlrlfpiamrlervckkdveingmfipkgvvvmipsyalhrdpk
ywtepekflperfskknkdnidpyiytpfgsgprncigmrfalmnmklalirvlqnfsfk
pcketqiplklslggllqpekpvvlkvesrdgt

SCOPe Domain Coordinates for d1w0ea_:

Click to download the PDB-style file with coordinates for d1w0ea_.
(The format of our PDB-style files is described here.)

Timeline for d1w0ea_: