SCOPe 2.01: Domain d1vywc_: 1vyw C:

Lineage for d1vywc_ (1vyw C:)

1. Root: SCOPe 2.01

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Cyclin-dependent PK, CDK2 [88855] (2 species)
   CMGC group; CDKs subfamily; serine/threonine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [88856] (204 PDB entries)
   Uniprot P24941

8. Domain d1vywc_: 1vyw C: [108925]
   Other proteins in same PDB: d1vywb1, d1vywb2, d1vywd1, d1vywd2
   complexed with 292, so4

Details for d1vywc_

PDB Entry: 1vyw, 2.3 Å

PDB Description: structure of cdk2/cyclin a with pnu-292137

PDB Compounds: (C:) Cell division protein kinase 2

SCOPe Domain Sequences for d1vywc_:

Sequence; same for both SEQRES and ATOM records:

>d1vywc_ d.144.1.7 (C:) Cyclin-dependent PK, CDK2 {Human (Homo sapiens) [TaxId: 9606]}
dmenfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkeln
hpnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafch
shrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgcky
ystavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykps
fpkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl

Timeline for d1vywc_:

• d1vywc_ first appeared in SCOP 1.69
  
• d1vywc_ appears in SCOP 1.75
  
• d1vywc_ appears in SCOPe 2.02
  
• d1vywc_ appears in the current release, SCOPe 2.08, called d1vywc1