SCOPe 2.08: Domain d1vkoa1: 1vko A:11-314,A:429-521

Lineage for d1vkoa1 (1vko A:11-314,A:429-521)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.3: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain [51800] (22 proteins)
   family members also share a common alpha+beta fold in C-terminal domain

6. Protein Myo-inositol 1-phosphate synthase [75105] (4 species)

7. Species Nematode (Caenorhabditis elegans) [TaxId:6239] [110419] (1 PDB entry)
   Uniprot Q18664

8. Domain d1vkoa1: 1vko A:11-314,A:429-521 [108684]
   Other proteins in same PDB: d1vkoa2
   Structural genomics target
   complexed with cl, iod, k, nad, pop
   has additional subdomain(s) that are not in the common domain

Details for d1vkoa1

PDB Entry: 1vko, 2.3 Å

PDB Description: crystal structure of inositol-3-phosphate synthase (ce21227) from caenorhabditis elegans at 2.30 a resolution

PDB Compounds: (A:) Inositol-3-phosphate synthase

SCOPe Domain Sequences for d1vkoa1:

Sequence; same for both SEQRES and ATOM records:

>d1vkoa1 c.2.1.3 (A:11-314,A:429-521) Myo-inositol 1-phosphate synthase {Nematode (Caenorhabditis elegans) [TaxId: 6239]}
krlivespnvkledgvlesrftyrknhfehradglhvtpkehdysfktvlkprktglllv
glggnngstavgsifanqyamtwrtkeghsqanyfgsvtqtatvhlgydsatqnqifvpf
kdivpilspndliisgwdisdsnlyeamgrakvfepelqeklrpfmepivplpsiyypdf
iasnqgdrannvipgdnklehlehiradirkfkqehelecvivlwtanterytdvrqgln
atadeimesirvnedevspsnifavasilegahyingspqntlvpglielaerhkvfvgg
ddfkXsllaspliydlailtelasrvsykvddeykpfhsvlsilslllkapvvppgtpis
nafmrqfstltklvtalagfpsdtdmqiefftqlpaak

Timeline for d1vkoa1:

• d1vkoa1 first appeared in SCOP 1.69
  
• d1vkoa1 appears in SCOPe 2.07