SCOP 1.73: Domain d1v3ua2: 1v3u A:113-294

Lineage for d1v3ua2 (1v3u A:113-294)

1. Root: SCOP 1.73

2. Class c: Alpha and beta proteins (a/b) [51349] (141 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (12 families)

5. Family c.2.1.1: Alcohol dehydrogenase-like, C-terminal domain [51736] (16 proteins)
   N-terminal all-beta domain defines family

6. Protein Leukotriene b4 12-hydroxydehydrogenase/prostaglandin 15-keto reductase [110405] (1 species)

7. Species Guinea pig (Cavia porcellus) [TaxId:10141] [110406] (4 PDB entries)

8. Domain d1v3ua2: 1v3u A:113-294 [108342]
   Other proteins in same PDB: d1v3ua1, d1v3ub1

Details for d1v3ua2

PDB Entry: 1v3u, 2 Å

PDB Description: Crystal structure of leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase in apo form

PDB Compounds: (A:) leukotriene b4 12-hydroxydehydrogenase/prostaglandin 15-keto reductase

SCOP Domain Sequences for d1v3ua2:

Sequence, based on SEQRES records:

>d1v3ua2 c.2.1.1 (A:113-294) Leukotriene b4 12-hydroxydehydrogenase/prostaglandin 15-keto reductase {Guinea pig (Cavia porcellus) [TaxId: 10141]}
lplslalgtigmpgltayfgllevcgvkggetvlvsaaagavgsvvgqiaklkgckvvga
agsdekiaylkqigfdaafnyktvnsleealkkaspdgydcyfdnvggeflntvlsqmkd
fgkiaicgaisvynrmdqlppgpspesiiykqlriegfivyrwqgdvrekalrdlmkwvl
eg

Sequence, based on observed residues (ATOM records):

>d1v3ua2 c.2.1.1 (A:113-294) Leukotriene b4 12-hydroxydehydrogenase/prostaglandin 15-keto reductase {Guinea pig (Cavia porcellus) [TaxId: 10141]}
lplslalgtigmpgltayfgllevcgvkggetvlvsaaagavgsvvgqiaklkgckvvga
agsdekiaylkqigfdaafnyktvnsleealkkaspdgydcyfdnvggeflntvlsqmkd
fgkiaicgaislppgpspesiiykqlriegfivyrwqgdvrekalrdlmkwvleg

Timeline for d1v3ua2:

• d1v3ua2 first appeared in SCOP 1.69
  
• d1v3ua2 appears in SCOP 1.71
  
• d1v3ua2 appears in SCOP 1.75
  
• d1v3ua2 appears in the current release, SCOPe 2.08