SCOP 1.75: Domain d1v35b_: 1v35 B:

Lineage for d1v35b_ (1v35 B:)

1. Root: SCOP 1.75

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (12 families)

5. Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (70 proteins)
   also known as short-chain dehydrogenases and SDR family
   parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7

6. Protein Enoyl-ACP reductase [51791] (6 species)

7. Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] [82296] (15 PDB entries)
   Uniprot Q9BJJ9 96-424 # fragment

8. Domain d1v35b_: 1v35 B: [108302]
   complexed with nai

Details for d1v35b_

PDB Entry: 1v35, 2.5 Å

PDB Description: crystal structure of eoyl-acp reductase with nadh

PDB Compounds: (B:) Enoyl-ACP reductase

SCOP Domain Sequences for d1v35b_:

Sequence, based on SEQRES records:

>d1v35b_ c.2.1.2 (B:) Enoyl-ACP reductase {Malaria parasite (Plasmodium falciparum) [TaxId: 5833]}
nedicfiagigdtngygwgiakelskrnvkiifgiwppvynifmknykngkfdndmiidk
dkkmnildmlpfdasfdtandideetknnkrynmlqnytiedvanlihqkygkinmlvhs
lanakevqkdllntsrkgyldalskssyslislckyfvnimkpqssiisltyhasqkvvp
gygggmssakaalesdtrvlayhlgrnynirintisagplksraatainklnntyenntn
qnknrnrhdvhnimnnsgekeekkisasqnytfidyaieysekyaplrqkllstdigsva
sfllsresraitgqtiyvdnglnimflpd

Sequence, based on observed residues (ATOM records):

>d1v35b_ c.2.1.2 (B:) Enoyl-ACP reductase {Malaria parasite (Plasmodium falciparum) [TaxId: 5833]}
nedicfiagigdtngygwgiakelskrnvkiifgiwppvynifmknykngkfdndmiidk
dkkmnildmlpfdasfdtandideetknnkrynmlqnytiedvanlihqkygkinmlvhs
lanakevqkdllntsrkgyldalskssyslislckyfvnimkpqssiisltyhasqkvvp
gygggmssakaalesdtrvlayhlgrnynirintisagplksraataintfidyaieyse
kyaplrqkllstdigsvasfllsresraitgqtiyvdnglnimflpd

Timeline for d1v35b_:

• d1v35b_ first appeared in SCOP 1.69
  
• d1v35b_ appears in SCOP 1.73
  
• d1v35b_ appears in SCOPe 2.01
  
• d1v35b_ appears in the current release, SCOPe 2.08