SCOP 1.75: Domain d1um2a3: 1um2 A:582-698

Lineage for d1um2a3 (1um2 A:582-698)

1. Root: SCOP 1.75

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.95: Homing endonuclease-like [55603] (2 superfamilies)
   alpha-beta(2)-alpha-beta(2)-alpha; 2 layers: a/b; antiparallel sheet 1243

4. Superfamily d.95.2: Homing endonucleases [55608] (2 families)

5. Family d.95.2.2: Intein endonuclease [55614] (2 proteins)
   duplication: contains tandem repeat of this fold

6. Protein VMA1-derived endonuclease (VDE) PI-SceI [55615] (1 species)
   homing endonuclease with protein splicing activity

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [55616] (7 PDB entries)
   Uniprot P17255 284-737

8. Domain d1um2a3: 1um2 A:582-698 [107948]
   Other proteins in same PDB: d1um2a1, d1um2b1

Details for d1um2a3

PDB Entry: 1um2, 2.9 Å

PDB Description: crystal structure of the vma1-derived endonuclease with the ligated extein segment

PDB Compounds: (A:) endonuclease pi-scei

SCOP Domain Sequences for d1um2a3:

Sequence, based on SEQRES records:

>d1um2a3 d.95.2.2 (A:582-698) VMA1-derived endonuclease (VDE) PI-SceI {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
gvknipsflstdnigtretflaglidsdgyvtdehgikatiktihtsvrdglvslarslg
lvvsvnaepakvdmngtkhkisyaiymsggdvllnvlskcagskkfrpapaaafare

Sequence, based on observed residues (ATOM records):

>d1um2a3 d.95.2.2 (A:582-698) VMA1-derived endonuclease (VDE) PI-SceI {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
gvknipsflstdnigtretflaglidsdgyvtdehgikatiktihtsvrdglvslarslg
lvvsvnaepisyaiymsggdvllnvlskcagskkfrpapaaafare

Timeline for d1um2a3:

• d1um2a3 first appeared in SCOP 1.69
  
• d1um2a3 appears in SCOP 1.73
  
• d1um2a3 appears in SCOPe 2.01
  
• d1um2a3 appears in the current release, SCOPe 2.08