SCOP 1.69: Domain d1uk1b1: 1uk1 B:662-798

Lineage for d1uk1b1 (1uk1 B:662-798)

1. Root: SCOP 1.69

2. Class a: All alpha proteins [46456] (218 folds)

3. Fold a.41: Domain of poly(ADP-ribose) polymerase [47586] (1 superfamily)
   core: 4 helices: bundle; unusual topology

4. Superfamily a.41.1: Domain of poly(ADP-ribose) polymerase [47587] (1 family)
   duplication: consists of 2 helix-loop-helix structural repeats

5. Family a.41.1.1: Domain of poly(ADP-ribose) polymerase [47588] (1 protein)

6. Protein Domain of poly(ADP-ribose) polymerase [47589] (3 species)

7. Species Human (Homo sapiens) [TaxId:9606] [101198] (2 PDB entries)

8. Domain d1uk1b1: 1uk1 B:662-798 [107903]
   Other proteins in same PDB: d1uk1a2, d1uk1b2

Details for d1uk1b1

PDB Entry: 1uk1, 3 Å

PDB Description: Crystal structure of human poly(ADP-ribose) polymerase complexed with a potent inhibitor

SCOP Domain Sequences for d1uk1b1:

Sequence; same for both SEQRES and ATOM records:

>d1uk1b1 a.41.1.1 (B:662-798) Domain of poly(ADP-ribose) polymerase {Human (Homo sapiens)}
ksklpkpvqdlikmifdvesmkkamveyeidlqkmplgklskrqiqaaysilsevqqavs
qgssdsqildlsnrfytliphdfgmkkppllnnadsvqakvemldnlldievaysllrgg
sddsskdpidvnyeklk

Timeline for d1uk1b1:

• d1uk1b1 is new in SCOP 1.69
  
• d1uk1b1 appears in SCOP 1.71
  
• d1uk1b1 appears in the current release, SCOPe 2.08