SCOP 1.75: Domain d1uhlb_: 1uhl B:

Lineage for d1uhlb_ (1uhl B:)

1. Root: SCOP 1.75

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (1 family)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (33 proteins)

6. Protein Oxysterols receptor LXR-alpha [109988] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [109989] (1 PDB entry)
   Uniprot Q13133 207-445

8. Domain d1uhlb_: 1uhl B: [107850]
   Other proteins in same PDB: d1uhla_
   complexed with 444, mei

Details for d1uhlb_

PDB Entry: 1uhl, 2.9 Å

PDB Description: crystal structure of the lxralfa-rxrbeta lbd heterodimer

PDB Compounds: (B:) Oxysterols receptor LXR-alpha

SCOP Domain Sequences for d1uhlb_:

Sequence, based on SEQRES records:

>d1uhlb_ a.123.1.1 (B:) Oxysterols receptor LXR-alpha {Human (Homo sapiens) [TaxId: 9606]}
mspeqlgmieklvaaqqqcnrrsfsdrlrvtpwpmapdphsrearqqrfahftelaivsv
qeivdfakqlpgflqlsredqiallktsaievmlletsrrynpgsesitflkdfsynred
fakaglqvefinpifefsramnelqlndaefalliaisifsadrpnvqdqlqverlqhty
vealhayvsihhphdrlmfprmlmklvslrtlssvhseqvfalrlqdkklppllseiwdv

Sequence, based on observed residues (ATOM records):

>d1uhlb_ a.123.1.1 (B:) Oxysterols receptor LXR-alpha {Human (Homo sapiens) [TaxId: 9606]}
mspeqlgmieklvaaqqqcnrrsfearqqrfahftelaivsvqeivdfakqlpgflqlsr
edqiallktsaievmlletsrrynpgsesitdfsynredfakaglqvefinpifefsram
nelqlndaefalliaisifsadrpnvqdqlqverlqhtyvealhayvsihhphdrlmfpr
mlmklvslrtlssvhseqvfalrlqdkklppllseiwdv

Timeline for d1uhlb_:

• d1uhlb_ first appeared in SCOP 1.69
  
• d1uhlb_ appears in SCOP 1.73
  
• d1uhlb_ appears in SCOPe 2.01
  
• d1uhlb_ appears in the current release, SCOPe 2.08, called d1uhlb1