Lineage for d1u59a_ (1u59 A:)

  1. Root: SCOP 1.71
  2. 595667Class d: Alpha and beta proteins (a+b) [53931] (286 folds)
  3. 611837Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 611838Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (7 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 611879Family d.144.1.7: Protein kinases, catalytic subunit [88854] (60 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 612447Protein Tyrosine-protein kinase ZAP-70 [111198] (1 species)
    PTK group; SYK/ZAP-70 subfamily; non-membrane spanning protein tyrosine kinase
  7. 612448Species Human (Homo sapiens) [TaxId:9606] [111199] (1 PDB entry)
  8. 612449Domain d1u59a_: 1u59 A: [107681]
    complexed with sto

Details for d1u59a_

PDB Entry: 1u59 (more details), 2.3 Å

PDB Description: crystal structure of the zap-70 kinase domain in complex with staurosporine

SCOP Domain Sequences for d1u59a_:

Sequence, based on SEQRES records: (download)

>d1u59a_ d.144.1.7 (A:) Tyrosine-protein kinase ZAP-70 {Human (Homo sapiens)}
kklflkrdnlliadielgcgnfgsvrqgvyrmrkkqidvaikvlkqgtekadteemmrea
qimhqldnpyivrligvcqaealmlvmemagggplhkflvgkreeipvsnvaellhqvsm
gmkyleeknfvhrdlaarnvllvnrhyakisdfglskalgaddsyytarsagkwplkwya
pecinfrkfssrsdvwsygvtmwealsygqkpykkmkgpevmafieqgkrmecppecppe
lyalmsdcwiykwedrpdfltveqrmracyyslaskveghhhhhh

Sequence, based on observed residues (ATOM records): (download)

>d1u59a_ d.144.1.7 (A:) Tyrosine-protein kinase ZAP-70 {Human (Homo sapiens)}
kklflkrdnlliadielgcgnfgsvrqgvyrkqidvaikvlkqgtekadteemmreaqim
hqldnpyivrligvcqaealmlvmemagggplhkflvgkreeipvsnvaellhqvsmgmk
yleeknfvhrdlaarnvllvnrhyakisdfglskalgaddsyytarsagkwplkwyapec
infrkfssrsdvwsygvtmwealsygqkpykkmkgpevmafieqgkrmecppecppelya
lmsdcwiykwedrpdfltveqrmracyyslaskveghhhhhh

SCOP Domain Coordinates for d1u59a_:

Click to download the PDB-style file with coordinates for d1u59a_.
(The format of our PDB-style files is described here.)

Timeline for d1u59a_: