SCOP 1.69: Domain d1u2zb_: 1u2z B:

Lineage for d1u2zb_ (1u2z B:)

1. Root: SCOP 1.69

2. Class c: Alpha and beta proteins (a/b) [51349] (136 folds)

3. Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest

4. Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (39 families)

5. Family c.66.1.31: Catalytic, N-terminal domain of histone methyltransferase Dot1l [89746] (1 protein)

6. Protein Catalytic, N-terminal domain of histone methyltransferase Dot1l [89747] (2 species)
   a non-SET domain nucleosomal histone methyltransferase

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [110667] (1 PDB entry)

8. Domain d1u2zb_: 1u2z B: [107627]

Details for d1u2zb_

PDB Entry: 1u2z, 2.2 Å

PDB Description: Crystal structure of histone K79 methyltransferase Dot1p from yeast

SCOP Domain Sequences for d1u2zb_:

Sequence, based on SEQRES records:

>d1u2zb_ c.66.1.31 (B:) Catalytic, N-terminal domain of histone methyltransferase Dot1l {Baker's yeast (Saccharomyces cerevisiae)}
stfvdwngpclrlqyplfdieylrsheiysgtpiqsislrtnspqptsltsdndtssvtt
aklqsilfsnymeeykvdfkrstaiynpmseigklieysclvflpspyaeqlketilpdl
nasfdnsdtkgfvnainlynkmireiprqriidhletidkiprsfihdflhivytrsihp
qanklkhykafsnyvygellpnflsdvyqqcqlkkgdtfmdlgsgvgncvvqaalecgca
lsfgceimddasdltilqyeelkkrcklygmrlnnvefslkksfvdnnrvaelipqcdvi
lvnnflfdedlnkkvekilqtakvgckiislkslrsltyqinfynvenifnrlkvqrydl
kedsvswthsggeyyistvmedvdeslfspaargrrnrgtpvkyt

Sequence, based on observed residues (ATOM records):

>d1u2zb_ c.66.1.31 (B:) Catalytic, N-terminal domain of histone methyltransferase Dot1l {Baker's yeast (Saccharomyces cerevisiae)}
stfvdwngpclrlqyplfdieylrsheiysgtpiqsislrtttaklqsilfsnymeeykv
dfkrstaiynpmseigklieysclvflpspyaeqlketilpdlnasfdnsdtkgfvnain
lynkmireiprqriidhletidkiprsfihdflhivytrsihpqanklkhykafsnyvyg
ellpnflsdvyqqcqlkkgdtfmdlgsgvgncvvqaalecgcalsfgceimddasdltil
qyeelkkrcklygmrlnnvefslkksfvdnnrvaelipqcdvilvnnflfdedlnkkvek
ilqtakvgckiislkslrsltyqinfynvenifnrlkvqrydlkedsvswthsggeyyis
tvmedvdeslfsprpvkyt

Timeline for d1u2zb_:

• d1u2zb_ is new in SCOP 1.69
  
• d1u2zb_ appears in SCOP 1.71
  
• d1u2zb_ appears in the current release, SCOPe 2.08